Background Intravenous thrombolysis (IVT) plays a prominent role in the treatment of acute
ischemic stroke (AIS). The sooner IVT is administered, the higher the odds of a good …

Background: The clinical benefit of intravenous thrombolysis (IVT) in acute ischemic stroke is
time dependent. Several studies report a short median door-to-needle time (DNT; 20 min) …

Objective: Pre-hospital, in-hospital, and patient factors are associated with variation in door
to needle (DTN) time in acute ischemic stroke (AIS). Publications are usually from large …

Background and Purpose—Shortening door-to-needle time (DNT) for the thrombolytic
treatment of stroke can improve treatment efficacy by reducing onset-to-treatment time. The …

Background Door to needle (DTN) time provides valuable insight into stroke care workflow
and is a performance indicator of an acute stroke unit. The aim of the current study was to …

Background: The clinical benefit of intravenous (IV) alteplase in acute ischemic stroke is time
dependent. We assessed the overall temporal changes in door-to-needle (DTN) time and …

Background and Purpose—Inverse relationship between onset-to-door time (ODT) and door-
to-needle time (DNT) in stroke thrombolysis was reported from various registries. We …

Background This study aimed to identify which emergency department (ED) factors impact
door-to-needle (DTN) time in acute stroke patients eligible for intravenous thrombolysis. The …

Background: In patients with acute ischemic stroke, early treatment with recombinant tissue
plasminogen activator (rtPA) improves functional outcome by effectively reducing disability …

The aim of this study was to reduce the door-to-needle (DTN) time of intravenous
thrombolysis (IVT) in acute ischemic stroke (AIS) through a comprehensive, hospital-based …