Historical and Molecular Perspectives on the Presence of Helicobacter pylori in Latin America: A Niche to Improve Gastric Cancer Risk Assessment

R González-Stegmaier, P Aguila-Torres… - International Journal of …, 2024 - mdpi.com
Helicobacter pylori (H. pylori) is responsible for causing chronic gastritis, which can cause
peptic ulcer and premalignant lesions such as atrophic gastritis, intestinal metaplasia, and …

Phylogeographic origin of Helicobacter pylori is a determinant of gastric cancer risk

T de Sablet, MB Piazuelo, CL Shaffer, BG Schneider… - Gut, 2011 - gut.bmj.com
Background and aims Helicobacter pylori colonises the stomach in half of all humans, and is
the principal cause of gastric cancer, the second leading cause of cancer death worldwide …

The Helicobacter pylori genome evolution in different gastric cancer risk Colombian populations

K Guzman, L Montenegro, A Pazos - 2021 - researchsquare.com
Background The Helicobacter pylori (H. pylori) has evolved with its human host by nearly
110,000 years. Despite that H. pylori has been considered as a main factor for gastric cancer …

Virulence-associated genotypes of Helicobacter pylori: do they explain the African enigma?

LE Bravo, LJ van Doorn, JL Realpe, P Correa - The American journal of …, 2002 - Elsevier
OBJECTIVES: The aim of this study was to compare the distribution of virulence-associated
genotypes of Helicobacter pylori in two Colombian populations with contrasting gastric …

Human and Helicobacter pylori coevolution shapes the risk of gastric disease

N Kodaman, A Pazos, BG Schneider… - Proceedings of the …, 2014 - National Acad Sciences
Helicobacter pylori is the principal cause of gastric cancer, the second leading cause of
cancer mortality worldwide. However, H. pylori prevalence generally does not predict cancer …

Helicobacter pylori Genotyping and Sequencing Using Paraffin‐Embedded Biopsies from Residents of Colombian Areas with Contrasting Gastric Cancer Risks

LA Sicinschi, P Correa, RM Peek Jr… - …, 2008 - Wiley Online Library
Background: cagA‐positive and vacA s1 and m1 genotypes of Helicobacter pylori are
associated with an elevated risk of gastric cancer (GC). We determined these genotypes …

[HTML][HTML] Whole Genome Sequence and Phylogenetic Analysis Show Helicobacter pylori Strains from Latin America Have Followed a Unique Evolution Pathway

ZY Munoz-Ramirez, A Mendez-Tenorio… - Frontiers in cellular …, 2017 - frontiersin.org
Helicobacter pylori (HP) genetics may determine its clinical outcomes. Despite high
prevalence of HP infection in Latin America (LA), there have been no phylogenetic studies in …

[HTML][HTML] Relatedness of Helicobacter pylori populations to gastric carcinogenesis

QJ Dong, SH Zhan, LL Wang, YN Xin… - World journal of …, 2012 - ncbi.nlm.nih.gov
Helicobacter pylori (H. pylori) is a Gram-negative bacterium that infects half of the human
population. The infection is associated with chronic inflammation of the gastric mucosa and …

Helicobacter pylori‐related risk predictors of gastric cancer: The latest models, challenges, and future prospects

SZ Bakhti, S Latifi‐Navid, R Safaralizadeh - Cancer medicine, 2020 - Wiley Online Library
Helicobacter pylori is known as an important determinant of preneoplastic lesions or gastric
cancer (GC) risk. The bacterial genotypes may determine the clinical outcomes. However …

Helicobacter pylori from Gastric Cancer and Duodenal Ulcer Show Same Phylogeographic Origin in the Andean Region in Colombia

S Shiota, R Suzuki, Y Matsuo, M Miftahussurur… - PloS one, 2014 - journals.plos.org
Background A recent report has shown that the phylogenetic origin of Helicobacter pylori
based on multi-locus sequence typing (MLST) was significantly associated with the severity …