We have demonstrated previously that activation of either the ET A or ET B receptor can
induce acute electrographic seizures following the intrahippocampal infusion of endothelin …

The period around birth is a risky time for stroke in infants, which is associated with two
major acute and subacute processes: anatomical damage and seizures. It is unclear as to …

The goal of this study was to develop a new model of ischemia‐induced seizures in
immature rats using injection of vasoconstrictor Endothelin‐1 (ET‐1) into the brain. ET‐1 (10 …

The direct injection of endothelin‐1 (ET‐1) into brain parenchyma was recently suggested
as a suitable model of stroke. The present study was designed to assess whether …

The aim was to test the hypothesis that occlusion of the middle cerebral artery (MCA) results
in the development of epilepsy in rats. Further, we investigated whether lesion volume …

We examined endothelin (ET) receptors in the hippocampus CA1 subfields of stroke‐prone
spontaneously hypertensive rats subjected to a 10‐min bilateral carotid occlusion and …

Background and Purpose—Elevated levels of endothelin-1 (ET-1) have been reported in
cerebral ischemia. A role for ET may prove more important if the vascular receptors were …

Endothelin-l (ET-1) mRNA has been found to be widely expressed not only in the rodent
brain but also within the human central nervous system (CNS)(1, 2). In view of the potent …

This work aimed to define the spatial expression of endothelin A (ETA) and B (ETB)
receptors in the cerebral cortex after permanent middle cerebral artery occlusion (MCAO) …

Abstract Endothelin-1 (ET-1) is recognized as being involved in the pathophysiology of
cerebrovascular diseases. Using organ culture as a model for possible pathological …