[PDF][PDF] Serum C-peptide level correlates with the course of muscle tissue healing in the rabbit model of critical limb ischemia.

Z Tauber, K Cizkova, M Janikova… - … Papers of the …, 2019 - biomed.papers.upol.cz
Aim. The therapeutic potential of adipose-derived stem cell conditioned medium (ASC-CM)
was studied in the rabbit model of critical limb ischemia (CLI). Methods. Rabbits received …

Phase I trial: the use of autologous cultured adipose-derived stroma/stem cells to treat patients with non-revascularizable critical limb ischemia

A Bura, V Planat-Benard, P Bourin, JS Silvestre… - Cytotherapy, 2014 - Elsevier
Background aims Non-revascularizable critical limb ischemia (CLI) is the most severe stage
of peripheral arterial disease, with no therapeutic option. Extensive preclinical studies have …

Therapeutic potential of adipose-derived therapeutic factor concentrate for treating critical limb ischemia

V Procházka, J Jurčíková, O Laššák… - Cell …, 2016 - journals.sagepub.com
Transplantation of adipose-derived stem cells (ADSCs) is an emerging therapeutic option for
addressing intractable diseases such as critical limb ischemia (CLI). Evidence suggests that …

Effect of C-peptide on wound healing and microcirculation in diabetic mice.

S Langer, F Born, A Breidenbach… - European journal of …, 2002 - europepmc.org
Aim Recent studies have demonstrated that C-peptide is biologically active and might have
a beneficial effect on late complications in diabetes mellitus. The aim of this study was to …

[HTML][HTML] Adipose tissue-derived stromal cells stimulated macrophages-endothelial cells interactions promote effective ischemic muscle neovascularization

J Czapla, T Cichoń, E Pilny, M Jarosz-Biej… - European Journal of …, 2020 - Elsevier
Neovascularization, the process of new blood vessels formation in response to hypoxia
induced signals, is an essential step during wound healing or ischemia repair. It follows as a …

[HTML][HTML] Adipose derived stem cell transplantation is better than bone marrow mesenchymal stem cell transplantation in treating hindlimb ischemia in mice

NB Vu, LT Phi, TTT Dao, HTN Le, VT Ta… - … Research and Therapy, 2016 - Springer
Abstract Introduction: Bone marrow derived MSCs (BM-MSCs) and adipose derived MSCs
(AD-MSCs) are among the types of stem cells most commonly studied. Our study aims to …

Adipose-derived stem cells ameliorate ischemia-reperfusion injury in a rat skin free flap model

A Ballestín, JG Casado, E Abellán… - Journal of …, 2018 - thieme-connect.com
Background Ischemia-reperfusion (I/R) injury is inevitable during free tissue transfers. When
the period of ischemia exceeds the tissue tolerance, it causes necrosis and flap failure. The …

Comparative study of mouse adipose-and bone marrow mesenchymal stem cells in diabetic model with critical limb ischemia

SL Asadi-Yousefabad, P Nammian, MH Sheikhha… - Cell and Tissue …, 2022 - Springer
The aim of this research is to compare the capabilities of Adipose tissue mesenchymal stem
cells (AT-MSCs) and bone marrow mesenchymal stem cells (BM-MSCs) in the treatment of …

Micronized cellular adipose matrix as a therapeutic injectable for diabetic ulcer

J Feng, K Doi, S Kuno, K Mineda, H Kato… - Regenerative …, 2015 - Future Medicine
Background: Despite the clinical potential of adipose-derived stem/stromal cells (ASCs),
there are some clinical difficulties due to the regulation of cell therapies. Materials & …

[HTML][HTML] Influence of autologous bone marrow fraction and simvastatin on microcirculation of leg muscles in experimental critical ischemia of the lower limbs

BS Sukovatykh, EE Feyziev… - Regional blood circulation …, 2021 - microcirc.ru
Introduction. The effectiveness of cell therapy at the stage of critical limb ischemia is
insufficient for regression of clinical manifestations of the ischemic process. Aim–to develop …