Cerebral autosomal recessive arteriopathy with subcortical infarcts and
leukoencephalopathy (CARASIL) is a heritable, rare small vessel disease, which is caused …

Background Biallelic HTRA1 pathogenic variants are associated with autosomal recessive
cerebral arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL). Recent …

Cerebral autosomal recessive arteriopathy with subcortical infarcts and
leukoencephalopathy (CARASIL) is a hereditary cerebral small vascular disease caused by …

Monogenic cerebral small vessel diseases are a topic of growing interest, as several genes
responsible have been recently described, and new sequencing techniques such as Next …

BACKGROUND: Cerebral small-vessel disease (cSVD) is an important cause of stroke and
vascular dementia. Most cases are multifactorial, but an emerging minority have a …

CADASIL is a rare and severe neurological disease which causes recurrent strokes,
dementia, and migraines. Mutations in the NOTCH3 gene are known to cause CADASIL …

Genetic stroke syndromes represent a small portion of stroke patients usually affecting
younger patients. Recognition of systemic manifestations of genetic disorders with stroke as …

CARASIL is a genetically determined disease related to vascular pathologies. A large
number of researchers have proven the presence of a mutation in the HTRA1 gene in …

Abstract Cerebral Autosomal Recessive Arteriopathy Subcortical Infracts
Leukoencephalopathy (CARASIL), is an autosomal recessive disorder inherited by two …

Aim: To establish a link between the development of CARASIL and mutations in the High-
TemperatureRequirement A1 gene. Materials and methods: Processed and studied 20 full …