Uncovering the Mechanisms of Adenosine Receptor-Mediated Pain Control: Focus on the A3 Receptor Subtype

E Coppi, F Cherchi, E Lucarini, C Ghelardini… - International Journal of …, 2021 - mdpi.com
… the mechanical allodynia induced by different rat models of … GABA decrease and preventing
mechanical allodynia (Figure 2B… of response to bortezomib-induced hyperalgesia in females …

TNF-α/STAT3 pathway epigenetically upregulates Nav1. 6 expression in DRG and contributes to neuropathic pain induced by L5-VRT

HH Ding, SB Zhang, YY Lv, C Ma, M Liu… - Journal of …, 2019 - Springer
… .6 upregulation in DRG neurons and mechanical allodynia induced by L5-VRT. … b The
fluorescence intensity by staining with anti-TNF-α antibody was lower in … Tumor necrosis factor-α

[PDF][PDF] Mechanism of aspirin-induced inhibition on the secondary hyperalgesia in osteoarthritis model rats

M Niibori, Y Kudo, T Hayakawa, K Ikoma-Seki… - Heliyon, 2020 - cell.com
Tumor necrosis factor-α (TNF-α) is upregulated in … or activity reduced thermal hyperalgesia
and mechanical allodynia [… In bortezomib-induced painful peripheral neuropathy model, TNF-…

Mechanisms of chemotherapy-induced peripheral neuropathy

R Zajączkowska, M Kocot-Kępska, W Leppert… - International journal of …, 2019 - mdpi.com
… pain and experimental animal models clearly show that the … An enhanced release of PIC
and subsequent decrease of … to the development of bortezomib-induced neuropathic pain, …

Chemokine signaling in chemotherapy-induced neuropathic pain

L Brandolini, M d'Angelo, A Antonosante… - International journal of …, 2019 - mdpi.com
… inflammatory mediators (interleukin (IL)-1β, tumor necrosis factor-α (TNF-α), bradykinin,
and … cortex of a rat model of depression [89]. Minocycline treatment decreased the marker of …

Multiple myeloma—a painful disease of the bone marrow

M Diaz-delCastillo, AD Chantry, MA Lawson… - Seminars in Cell & …, 2021 - Elsevier
Tumour necrosis factor α … Moreover, these treatments also reduced the overexpression of
neuronal excitation … Animal models of bortezomib-induced peripheral neuropathy include mice …

Non-hematologic toxicity of bortezomib in multiple myeloma: The neuromuscular and cardiovascular adverse effects

E Pancheri, V Guglielmi, GM Wilczynski, M Malatesta… - Cancers, 2020 - mdpi.com
… Conversely, in animal models of bortezomib-induced … heart of treated rats and a decreased
cell shortening of primary rat left … Due to the possible clinical relevance of bortezomib-induced

Comparison of chemotherapy effects on mechanical sensitivity and food-maintained operant responding in male and female rats

LP Legakis, CM Diester, EA Townsend… - Behavioural …, 2020 - journals.lww.com
… of bortezomib-induced mechanical hypersensitivity. … , rats had to press their orofacial regions
against a ring of von Frey-like filaments to receive the milk reinforcer, and the decreases in …

[HTML][HTML] Cannabinoids: an effective treatment for chemotherapy-induced peripheral neurotoxicity?

G Cavaletti, P Marmiroli, CL Renn, SG Dorsey… - …, 2021 - Elsevier
… Administration of CP55,940 decreased the migration of rat … Among the different forms of
CIPN, bortezomib-induced … Here we briefly report the results of a study performed in a rat model

Selective activation of metabotropic glutamate receptor 7 blocks paclitaxel-induced acute neuropathic pain and suppresses spinal glial reactivity in rats

J Wang, C Jiang, X Ba, S Yang, J Wu, Z Huang… - …, 2021 - Springer
… is mainly based on studies using animal model of chronic pain induced by … decreased
spinal glutamate level and prevented the onset of bortezomib-induced neuropathic pain in rats