… , in the most severe situations, intrauterine fetal death [3,4]. … The following facts support the
relevant role of sex hormones … enzyme may expose the fetus to increased concentrations of …

… were heterozygous for type 1 and homozygous for the type 2 [… Long-term oral administration
of 5alpha-reductase inhibitor … paracrine stimulation of endothelial cell growth by estrogens …

… The 5α-reductase type 1 isoform was upregulated with … estrogens and progestogens in
females are produced by the … in symptomatic SOD1 G93A mice without major disruptions to spinal …

… To understand how male mice lacking HSD17B3 … hormones. This revealed that, under
basal conditions, progesterone, 17‐OHP, and androstenedione are all significantly increased in …

… impaired placental function causing fetal demise before PTB [… in the murine cervix is
5alpha-reductase type 1 (Srd5a1) [128… favorable for increased expression of estrogen-dependent …

… -hydroxysteroid dehydrogenase type 1 and 5α-reductase type 1. … of sex steroid hormones
during critical perinatal periods can … All strains of mice lacking HSD11B1 have larger adrenals …

The gonads, the adrenals and in many mammal species also the placenta produce steroid
hormones. The production and function of gestagens and oestrogens are well documented …

… had increased insulin-like growth factor (Igf) type 1 (Igf1), Igf1… that specific hormones are
required for the regulation of fetal … neonatal demise in a global GR knockout (GRKO) mouse …

… 10 days of sensory or motor enrichment increased the 5α-R1 … Interestingly, in male rats, 5α-R
type 1 and type 2 expression … Indeed, although type 1 expression is limited in the brainstem…

… MK 2-amino-musk ketone 3-HSD 3-hydroxysteroid dehydrogenase 3b-HSD 3-beta-hydroxysteroid
dehydrogenase 3beta-HSD 3-beta-hydroxysteroid dehydrogenase 5alpha reductase …