… The antinociceptive effects of opiates are mediated, in part, through removal of GABA A -…
been indirectly investigating sex differences in immune-derived pain and analgesia for quite …

… Using the CFA model of chronic inflammatory pain, we evaluated peripheral immune-derived
endogenous opioid antinociception (6, 32–35) in WT and TRPV1 −/− mice by measuring …

… Immune-derived opioids exhibit anti-inflammatory activities in Th1/Th17-driven colitis because
of their propensity to favor the commitment of lymphocytes towards a Th2 phenotype [45,…

… and peripheral nervous system9 but is also expressed by immune cells, and immune-derived
β-… β-END released by immune cells might also exert antinociceptive and anti-inflammatory …

… that immune-derived opioids … immune-derived opioids may inhibit ENS activity during IBD,
and, therefore, their inhibition may worsen diarrhea, evidence that immune-derived opioids …

… Moreover, its analogy with the opioid system in terms of … antinociceptive fiber tracts as a
likely site and mechanism of action [25]. … Moreover, immune-derived factors might either induce …

… opioid system has also been obtained from inflammatory pain and immune-derived peripheral
antinociception … Indeed, it is known that the release of endogenous opioid peptides by …

… Furthermore, we discuss the antinociceptive effects related to an … Endogenous opioids and
opioid degrading enzymes … main source of immune derived β-endorphin in human peripheral …

… This antinociception may be because of certain bacteria, such as Lactobacillus reuteri
DSM … activation of opioid receptors on sensory nerves by immune-derived opioid peptides. …

… –17) opioid peptide produces antinociception following binding to the kappa-opioid peptide
(… and yields a unique set of opioid and non-opioid fragments. Some of these major fragments …