… (PK–PD) correlations through the integration of knowledge from multiple disciplines and …
and discovery of potential new drugs, especially TCM-related combination drug discovery. …

… to integrate the current knowledge on posaconazole pharmacokinetics, pharmacodynamics,
… therapeutic strategies in order to get a clear understanding of the clinical use of this drug. …

… within drug discovery. We require new capabilities and strategies of integrated imaging to
… Integrated molecular imaging and advanced image analysis have the opportunity to provide …

… While in vitro and non-human in vivo preclinical models have long been an integral
component in the history of drug development [4], they frequently fail to accurately predict a …

… with the pharmacokinetics of the drug. Hence, several attempts to integrate PK and residence
… Fisher laboratories have integrated compound PK rate constants with those for drug-target …

… setting (patient‐centric sampling), (iii) use of digital devices to collect and measure
physiological and behavioral data (digital biomarkers), and (iv) use of data platforms that integrate …

… To that end, we developed an in silico modeling approach in repurposing of CCBs and
ACEi compounds, using an AI-integrated mechanistic modeling platform by utilizing known …

… and begin realizing new opportunities in QSP and ML integration. The working group, which
… drug development decision making. The working group also concluded that the integration …

… various in silico ADMET tools in drug discovery and development process, and provides a
brief … of in silico tools and possible scope of integration with in vitro methods for enhancing the …

… natural source for drug discovery regarding COVID-19 … medicines have been reviewed and
considered promising prophylactic agents, treatments, or lead compounds for drug discovery …