… viral ion channels, in general, may be a good target for the development of antiviral agents,
and that, in particular, kaempferol glycosides are good candidates for 3a channel proteins of …

… in channel dysfunction. We review the structural features that underpin ion channel function
and how ion channels are … ion channel targets into the next generation of drug therapies. …

… the possible roles of ion channels and channelopathies as a therapeutic target in other viral
… of antiviral therapies aim to incorporate mechanisms within drugs that target ion channels. …

… Taken together, the data imply that the antiviral target of HMA is the E protein, and further,
that the E protein ion channel activity is important for coronavirus replication. Other groups …

… viral ion channels, in general, may be a good target for the development of antiviral agents.
… other viruses also encode for ion channels, our findings strengthens the view that viral ion …

… -α-based therapy but has not proven significant antiviral efficacy [85]. In conclusion, iminosugar
derivatives efficiently inhibited p7 ion channel activity in vitro and suppressed spread of …

… E5 oncoprotein forms a virus-coded ion channel or viroporin that was sensitive to the …
E5 channel activity represents a viable drug target with potential for both antiviral and anti-…

… We show that hepatitis C virus (HCV) p7 protein forms ion channels in black lipid membranes.
HCV p7 ion channels are inhibited … HCV p7 presents a potential target for antiviral therapy. …

… Due to the spontaneous mutations of these viral proteins, currently available antiviral and
anti-influenza drugs quickly develop resistance. To account this, only limited antiinfluenza …

… as ion channels on the viral membranes, similar to how they function in host cells, we
propose that 2-E channel may represent a new class of dual-function targets against SARS-CoV-2. …