… of the protective CD8 + T cells generated by this vaccination … cells could further improve
and prolong protective immunity … recognized by protective T cells would also improve both the …

… To obtain the best experience, we recommend you use a more … These early memory CD8
+ T cells underwent vigorous … effector and memory T cells and enhanced protective immunity. …

… Compared with naive T cells, memory T cells have a shorter … As we better understand the
mechanisms of memory … ability of vaccination to induce long-lasting protective immunity may in …

… whereby CD4 T cells can contribute to protective immune responses … of memory CD4 T
cells into vaccine strategies thus presents an attractive approach toward improving immunity …

… the protective immune responses following M. tuberculosis infection or vaccination, with a
particular focus on vaccines … with the MVA85A vaccine in humans, no improved protection over …

… protective immunity—the intended goal of vaccination. Indeed… of memory CD8+ T cells are
most potent for pathogen control. … protective immunity against acute pathogen infection is best …

… T cell memory and subsequent protective immunity (15–17). Thus, a better understanding of
vaccine-elicited T cell immunity … in mediating the T cell response to subunit vaccination, we …

… we develop better strategies to enhance vaccine design and … memory CD4 T cells
competing with naïve CD4 T cells … CD4 T cells elicited by the vaccine will promote production of …

… have implications for vaccination, especially in terms of determining the optimal time for
boosting. Because T CM cells proliferate substantially better than T EM cells upon reexposure to …

… -lasting, protective CD8 + T-cell memory via vaccination is … new insights into how memory
CD8 + T cells are generated. It … that T CM actually provide more effective protective immunity…