Novel surgical strategies have dramatically improved the initial outcome of newborns with
hypoplastic left heart syndrome. However, the single systemic right ventricle remains a major …

Single ventricle physiology, especially hypoplastic left heart syndrome, is one of the most
high-risk lesions in children with congenital heart disease, and the ensuing heart failure …

Hypoplastic left heart syndrome (HLHS) is a deadly congenital heart disease that arises
when the left ventricle and outflow tract fail to develop appropriately, inhibiting the adequate …

Objective We sought to define the intrinsic stem cell capacity in pediatric heart lesions, and
the effects of diagnosis and of age, in order to inform evidence-based use of potential …

Background: Congenital heart disease (CHD) constitutes the most prevalent and
heterogeneous group of congenital anomalies. Although surgery remains the gold standard …

Congenital heart disease (CHD) is the most prevalent congenital anomaly in newborn
babies. Cardiac malformations have been induced in different animal model experiments, by …

Hypoplastic left heart syndrome (HLHS) is a complex congenital heart disease in which a
neonate is born with an underdeveloped left ventricle and associated structures. Without …

This article reports on the evolving field of stem cell therapy and its impact on the
management of cardiac pathology, in particular congenital heart disease. To date, stem cell …

Heart failure remains the leading cause of death worldwide, and is a burgeoning problem in
public health due to the limited capacity of postnatal hearts to self-renew. The …

Pediatric heart failure (HF) is rare. The prognosis is generally poor. HF is most frequently
related to cardiomyopathy or congenital heart disease (CHD). Associated phenotypes are …