The MAP30 protein from bitter gourd (Momordica charantia) seeds promotes apoptosis in liver cancer cells in vitro and in vivo

EF Fang, CZY Zhang, JH Wong, JY Shen, CH Li, TB Ng - Cancer letters, 2012 - Elsevier
Human hepatocellular carcinoma Hep G2 cells and Hep G2-bearing mice were used as in
vitro and in vivo models to assess the efficacy and safety of MAP30, a natural component …

Bitter gourd (Momordica charantia) is a cornucopia of health: a review of its credited antidiabetic, anti-HIV, and antitumor properties

EF Fang, TB Ng - Current molecular medicine, 2011 - ingentaconnect.com
Bitter gourd (Momordica charantia, BG) is both a nutritious and healthy food with a distinctive
bitter flavor, and it is also widely exploited in folklore medicine. This review focuses on the …

Screening, discovery, and characterization of angiotensin-I converting enzyme inhibitory peptides derived from proteolytic hydrolysate of bitter melon seed proteins

AD Priyanto, RJ Doerksen, CI Chang, WC Sung… - Journal of …, 2015 - Elsevier
In this study, new angiotensin-I converting enzyme (ACE) inhibitory peptides were
comprehensively identified from a thermolysin digest of bitter melon (Momordica charantia) …

Ribosome inactivating proteins (RIPs) from Momordica charantia for anti viral therapy

M Puri, I Kaur, RK Kanwar, RC Gupta… - Current Molecular …, 2009 - ingentaconnect.com
This review describes the nature and applications of ribosome inactivating proteins (RIPs)
from Momordica charantia (bitter melon). RIPs from the plant kingdom have received much …

Structural and functional modeling of human lysozyme reveals a unique nonapeptide, HL9, with anti-HIV activity

S Lee-Huang, V Maiorov, PL Huang, A Ng, HC Lee… - Biochemistry, 2005 - ACS Publications
We previously reported that lysozyme accounts for anti-HIV activity associated with the β-
core fraction of human chorionic gonadotropin [Lee-Huang, S., Huang, PL, Sun, Y., Kung …

Immunomodulatory Activity and Partial Characterisation of Polysaccharides from Momordica charantia

YY Deng, Y Yi, LF Zhang, RF Zhang, Y Zhang, ZC Wei… - Molecules, 2014 - mdpi.com
Momordica charantia Linn. is used as an edible and medicinal vegetable in sub-tropical
areas. Until now, studies on its composition and related activities have been confined to …

[PDF][PDF] Momordica charantia Linn.(Karela): Nature's silent healer

M Gupta, S Sharma, AK Gautam… - International Journal of …, 2011 - researchgate.net
Momordica charantia Linn.(karela) is an herbal climber grown in tropical and subtropical
regions, belonging to the Cucurbitaceae family. Momordica charantia (Karela) have …

[HTML][HTML] Momordica charantia Extract Induces Apoptosis in Human Cancer Cells through Caspase- and Mitochondria-Dependent Pathways

CJ Li, SF Tsang, CH Tsai, HY Tsai… - Evidence-Based …, 2012 - hindawi.com
Plants are an invaluable source of potential new anti-cancer drugs. Momordica charantia is
one of these plants with both edible and medical value and reported to exhibit anticancer …

Which plant proteins are involved in antiviral defense? Review on in vivo and in vitro activities of selected plant proteins against viruses

O Musidlak, R Nawrot… - International Journal of …, 2017 - mdpi.com
Plants have evolved a variety of defense mechanisms to tackle virus attack. Endogenous
plant proteins can function as virus suppressors. Different types of proteins mediate defense …

[PDF][PDF] A review on salient pharmacological features of Momordica charantia

A Upadhyay, P Agrahari, DK Singh - Int J Pharmacol, 2015 - researchgate.net
ABSTRACT Plant Momordica charantia Linn., known as bitter gourd, belongs to family
Cucurbitaceae. It is cultivated throughout India, Malaya, China, Tropical Africa and America …