Fibroblasts can be directly reprogrammed into cardiomyocytes, endothelial cells or smooth
muscle cells. Here we report the reprogramming of mouse tail-tip fibroblasts simultaneously …

Rationale: Induced pluripotent stem cells (iPSCs) hold great promise for the development of
patient-specific therapies for cardiovascular disease. However, clinical translation will …

Human embryonic stem cell‐derived cardiomyocytes (hESC‐CMs) have become promising
tools to repair injured hearts. To achieve optimal outcomes, advanced molecular imaging …

Stem cell therapy in heart disease is challenged by mis-injection, poor survival, and low cell
retention. Here, we describe a biocompatible multifunctional silica–iron oxide nanoparticle …

Background—The arrangement of myofibers in the heart is highly complex and must be
replicated by injected cells to produce functional myocardium. A novel approach to …

Rationale: Molecular imaging has proven to be a vital tool in the characterization of stem cell
behavior in vivo. However, the integration of reporter genes has typically relied on random …

Stem cell therapy has broad applications in regenerative medicine and increasingly within
cardiovascular disease. Stem cells have emerged as a leading therapeutic option for many …

Over the past two decades cardiac cell therapy (CCT) has emerged as a promising new
strategy to cure heart diseases at high unmet need. Thousands of patients have entered …

Noninvasive reporter gene imaging is a component of molecular imaging. Reporter imaging
can provide noninvasive assessments of endogenous biologic processes in living subjects …

Molecular imaging has played an important role in the noninvasive exploration of multiple
biological processes. Reporter gene imaging is a key part of molecular imaging. By …