[HTML][HTML] Comparative metabolomic analysis of HPAC cells following the acquisition of erlotinib resistance

S Lee, WJ Jang, B Choi, SH Joo… - Oncology …, 2017 - spandidos-publications.com
… In the current study, erlotinib-resistant human pancreatic adenocarcinoma cells (… erlotinib.
To achieve this, the metabolic characteristics between erlotinib-sensitive (HPAC) and erlotinib-…

[HTML][HTML] Comparison of the inhibition potentials of icotinib and erlotinib against human UDP-glucuronosyltransferase 1A1

X Cheng, X Lv, H Qu, D Li, M Hu, W Guo, G Ge… - … Pharmaceutica Sinica B, 2017 - Elsevier
study focused on the investigation and comparison of the inhibitory effects of icotinib and
erlotinib … In this study, the inhibitory effects of icotinib and erlotinib against human UGT1A1 were …

UPLC–ESI–MS/MS study of the effect of green tea extract on the oral bioavailability of erlotinib and lapatinib in rats: Potential risk of pharmacokinetic interaction

HM Maher, NZ Alzoman, SM Shehata… - … of Chromatography B, 2017 - Elsevier
… The applicability of the method was extended to perform a comparative study of the PK of
ERL/LAP following short-term and long-term administration of GTE, compared with their single …

[HTML][HTML] Comparative of in-vitro evaluation between erlotinib loaded nanostructured lipid carriers and liposomes against A549 lung cancer cell line

FA Gaballu, S Abbaspour-Ravasjani… - Iranian journal of …, 2019 - ncbi.nlm.nih.gov
Erlotinib (ELT) as a small molecule with poor solubility, poor … In the present study, ELT-liposome
and ELT-NLCs were … The obtained data from this study clearly showed that ELT-NLCs …

Is there evidence for different effects among EGFR-TKIs? Systematic review and meta-analysis of EGFR tyrosine kinase inhibitors (TKIs) versus chemotherapy as first …

ER Haspinger, F Agustoni, V Torri, F Gelsomino… - Critical reviews in …, 2015 - Elsevier
… of erlotinib versus chemotherapy, then the estimate of the adjusted indirect comparison of
gefitinib versus erlotinib … other TKI-inhibitors could arise from the results of comparative studies. …

Conclusions of the expert panel: importance of erlotinib as a second-line therapeutic option

A Castagnari - BMC proceedings, 2008 - Springer
… , participants emphasized the usefulness of erlotinib as second-line therapy for lung cancer.
They noted that, although there are no comparative studies, erlotinib could be as effective as …

Dacomitinib versus erlotinib in patients with advanced-stage, previously treated non-small-cell lung cancer (ARCHER 1009): a randomised, double-blind, phase 3 trial

SS Ramalingam, PA Jänne, T Mok, K O'Byrne… - The lancet …, 2014 - thelancet.com
… compared with erlotinib. We aimed to compare dacomitinib with erlotinib in a phase 3 study.
… The availability of this new generation of EGFR inhibitors prompted comparative studies

Design of phase II cancer trials using a continuous endpoint of change in tumor size: application to a study of sorafenib and erlotinib in non–small-cell lung cancer

TG Karrison, ML Maitland, WM Stadler… - Journal of the National …, 2007 - academic.oup.com
… maintaining efficiency and reducing the number of subjects required for a comparative
study. This approach may offer advantages over conventional phase II cancer trial designs. …

Randomized phase II study of fulvestrant and erlotinib compared with erlotinib alone in patients with advanced or metastatic non-small cell lung cancer

EB Garon, JM Siegfried, LP Stabile, PA Young… - Lung Cancer, 2018 - Elsevier
… receiving erlotinib plus fulvestrant and 28 patients receiving erlotinib alone). Overall, the
median PFS was 3.5 months for erlotinib plus fulvestrant and 1.9 months for erlotinib alone [HR …

Inclusion complex of erlotinib with sulfobutyl ether-β-cyclodextrin: Preparation, characterization, in silico, in vitro and in vivo evaluation

N Devasari, CP Dora, C Singh, SR Paidi, V Kumar… - Carbohydrate …, 2015 - Elsevier
… The aim of the study was to investigate the impact of erlotinib … Preliminary comparative phase
solubility study indicated … silico computational study, employed to analyze the comparative