Hypertension and heart failure: prevention, targets, and treatment

KE Di Palo, NJ Barone - Heart failure clinics, 2020 - heartfailure.theclinics.com
… The complex nature of cardiac remodeling attributed to … of heart failure, in particular HFpEF,
than coronary artery … tended to be inferior to ACE inhibitors and ARBs. Secondary outcomes …

[HTML][HTML] Diabetic nephropathy: focusing on pathological signals, clinical treatment, and dietary regulation

Q Hu, Y Chen, X Deng, Y Li, X Ma, J Zeng… - Biomedicine & …, 2023 - Elsevier
diabetes and the most common cause of end-stage renal disease… Lisinopril (Table 1,
NCT00118976) is an ACE inhibitor that … demonstrated beneficial effects in a telmisartan therapy …

Targeting the NLRP3 inflammasome to treat cardiovascular fibrosis

AA Pinar, TE Scott, BM Huuskes, FET Caceres… - Pharmacology & …, 2020 - Elsevier
heart and blood vessels, including coronary artery disease, … HFpEF are adverse cardiac
remodelling and stiffening that … cardiomyopathies and in models of kidney disease. Of these, the …

[HTML][HTML] The impact of microRNAs in renin–angiotensin-system-induced cardiac remodelling

M Adamcova, I Kawano, F Simko - International Journal of Molecular …, 2021 - mdpi.com
… therapeutic success of ACE inhibitors and AT1R blockers. … cardiac remodelling,
especially in the context of renal injury. … A 12-month treatment with a combination of ARB (telmisartan

The role of the renin-angiotensin-aldosterone system in cardiovascular disease: pathogenetic insights and clinical implications

V Capric, HP Chandrakumar… - Renin-angiotensin …, 2021 - books.google.com
… role of RAAS in cardiac remodeling and heart failure [35–37]. … with complications and found
that the combination of telmisartanEffects of enalapril on mortality in severe congestive heart

Anti-diabetic effect of telmisartan through its partial PPARγ-agonistic activity

MA Ayza, KA Zewdie, BA Tesfaye… - Diabetes, Metabolic …, 2020 - Taylor & Francis
… responses in diabetic patients with coronary artery disease. … , thus preventing unfavorable
cardiac remodeling. Citation7 … of cardiovascular and renal function in patients with T2DM. …

[HTML][HTML] Effects of soluble guanylate cyclase stimulator on renal function in ZSF-1 model of diabetic nephropathy

L Hu, Y Chen, X Zhou, M Hoek, J Cox, K Lin, Y Liu… - Plos one, 2022 - journals.plos.org
… , however combination with telmisartan reduced urinary albumin … drug Enalapril to understand
the renal effects on function, … -binding complex and produce only an additive effect with NO…

[HTML][HTML] The Role of Renin–Angiotensin System in Diabetic Cardiomyopathy: A Narrative Review

JPT Batista, AOV Faria, TFS Ribeiro… - Life, 2023 - mdpi.com
… , found that the ACE inhibitor ramipril reduced the risk of … Cardiac remodeling can occur as
a result of the increased … with telmisartan also improved the balance between coronary blood …

[HTML][HTML] Overexpression of angiotensin-converting enzyme 2 by renin-angiotensin system inhibitors. Truth or myth? A systematic review of animal studies

H Kai, M Kai, H Niiyama, N Okina, M Sasaki… - Hypertension …, 2021 - nature.com
Renal ACE2 protein was unaffected by telmisartan or … One article showed that enalapril
restored cardiac mRNA from a … not change ACE2 immunointensity in coronary arteries at week 3, …

[PDF][PDF] Hypertension in diabetes

MD Sowjanya Naha, MJ Gardner… - Interventions, 2021 - endotext.org
… This hemodynamic effect is reno-protective in patients with diabetic kidney disease. An … of
aldosterone on cardiac remodeling. Addition of finerenone to patients receiving ACE inhibitors