Heterogenous patterns of sensory dysfunction in postherpetic neuralgia suggest multiple pathophysiologic mechanisms

M Pappagallo, AL Oaklander… - The Journal of the …, 2000 - pubs.asahq.org
… neuropathic pain, is a common sequela to herpes zoster (… between ongoing pain and
allodynia induced by a dynamic … neuropathic injuries in different strains of mice. 27Our results …

[HTML][HTML] Oxaliplatin treatment changes the function of sensory nerves in rats

S Yamamoto, H Ono, K Kume, M Ohsawa - Journal of pharmacological …, 2016 - Elsevier
… L-OHP-injected rats. Mechanical static allodynia, dynamic allodynia, and cold allodynia were
… we found no significant differences between L-OHP- and vehicle-treated groups (Fig. 3D). …

Glycine transport inhibitors for the treatment of pain

RJ Vandenberg, RM Ryan, JE Carland… - … in pharmacological …, 2014 - cell.com
pain relief but they do not provide adequate pain relief in a large proportion of chronic pain
… is impaired in chronic pain states, and this provides a novel target for drug development. …

Neuropathic pain: diagnosis, pathophysiological mechanisms, and treatment

R Baron, A Binder, G Wasner - The Lancet Neurology, 2010 - thelancet.com
… requires an interdisciplinary approach, centred around pharmacological treatment. A better
… with postherpetic neuralgia and 20% of all patients had mechanical dynamic allodynia. …

The Biology and Pharmacology of Calcium Channel α2‐δ Proteins Pfizer Satellite Symposium to the 2003 Society for Neuroscience Meeting Sheraton New Orleans …

CP Taylor - CNS drug reviews, 2004 - ncbi.nlm.nih.gov
… behavioral pharmacology of drug action, but entla mice have … for treatment of pain from
postherpetic neuralgia. Several … filaments (static allodynia) but not against allodynia from light …

What should we be measuring in behavioral studies of chronic pain in animals?

JS Mogil, SE Crager - Pain, 2004 - journals.lww.com
… severity, but significant tactile allodynia was an inclusion … of spontaneous chronic pain
is very likely different from the … useful, we would argue that drug development will not (and …

Systemic lidocaine in pain due to peripheral nerve injury and predictors of response

N Attal, J Rouaud, L Brasseur, M Chauvin… - Neurology, 2004 - AAN Enterprises
drug also decreased mechanical dynamic allodynia and static (punctate) mechanical
allodynia… For this purpose, we included patients with postherpetic neuralgia and traumatic nerve …

Gabapentin in pain management

J Mao, LL Chen - Anesthesia & Analgesia, 2000 - journals.lww.com
… in the right T4 dermatome three months after acute herpes … also decreased mechanical
allodynia in these same rats ( 32 )… a rational use of this drug in pain management. These issues …

[PDF][PDF] Gabapentin and pregabalin for the treatment of neuropathic pain: A review of laboratory and clinical evidence

I Gilron, SJL Flatters - Pain Research and Management, 2006 - downloads.hindawi.com
… effects occur because of drug interaction with the α2δ … same effects on pain behaviour in CCI
rats. Gabapentin partially … pain behaviours induced by streptozocin (24) and herpes zoster (…

Allodynia and hyperalgesia in neuropathic pain: clinical manifestations and mechanisms

TS Jensen, NB Finnerup - The Lancet Neurology, 2014 - thelancet.com
… reactions, with separate mechanisms in different subtypes of allodynia and hyperalgesia. …
Only 47% with postherpetic neuralgia had touch-evoked allodynia, although this is usually …