[HTML][HTML] The role of osteopontin in tumor progression through tumor-associated macrophages

Y Tan, L Zhao, YG Yang, W Liu - Frontiers in Oncology, 2022 - frontiersin.org
… and polarization, tumor angiogenesis, and tumor fibrosis … matrix degradation and absorption.
After macrophage depletion, the proportion of Sirius red-staining positive collagen matrix in …

The unique invasiveness of glioblastoma and possible drug targets on extracellular matrix

A Hatoum, R Mohammed, O Zakieh - Cancer management and …, 2019 - Taylor & Francis
… The best evidence is associated with MMP-9, initially implicated for its role in angiogenesis
tumor stem cells appropriately, despite these likely playing a major role in tumor progression

[HTML][HTML] COL5A1 serves as a biomarker of tumor progression and poor prognosis and may be a potential therapeutic target in gliomas

S Gu, Z Peng, Y Wu, Y Wang, D Lei, X Jiang… - Frontiers in …, 2021 - frontiersin.org
roles in the collagen hierarchy, was reported to promote progression and chemoresistance
and affect tumor-… ) and enhance glioma angiogenesis through HIF1α-VEGFR2 signaling (35). …

Proteoglycan signaling in tumor angiogenesis and endothelial cell autophagy

MA Gubbiotti, S Buraschi, A Kapoor, RV Iozzo - Seminars in cancer biology, 2020 - Elsevier
… more innovation in the coming years with advancement in patient prognosis and outcome. …
directly physiologic role. Using aortic ring assays as a proxy for tumor angiogenesis, current …

[HTML][HTML] Stromal cells in the tumor microenvironment: accomplices of tumor progression?

Y Zhao, M Shen, L Wu, H Yang, Y Yao, Q Yang… - Cell Death & …, 2023 - nature.com
… , participating in tumor angiogenesis and tumor metabolism, … in TME as well as the role and
specific mechanism of stromal … type I collagen content and significantly reduce tumor tissue …

[HTML][HTML] Lysyl oxidase family enzymes and their role in tumor progression

T Liburkin-Dan, S Toledano, G Neufeld - International Journal of …, 2022 - mdpi.com
tumor progression model, and induces desmoplasia and the deposition of thick collagen
bundles in tumors … in copper availability can inhibit tumor angiogenesis [54], suggesting that …

Emerging role of interactions between tumor angiogenesis and cancer stem cells

S Lv, Y Liu, C Xie, C Xue, S Du, J Yao - Journal of Controlled Release, 2023 - Elsevier
… for their critical roles in tumor progression, metastasis and … collagen, fibronectin, laminin,
proteoglycans, and matricellular proteins, which play important roles in both tumor angiogenesis

[HTML][HTML] RhoJ facilitates angiogenesis in glioblastoma via JNK/VEGFR2 mediated activation of PAK and ERK signaling pathways

M Wang, C Zhang, Q Zheng, Z Ma, M Qi… - … Journal of Biological …, 2022 - ncbi.nlm.nih.gov
… the importance of angiogenesis in the progression of GBM, … the vascular structure and
tumor angiogenesis 37 . The small … role in EC lumen formation in the 3D collagen matrix 44 . …

[HTML][HTML] microRNAs biogenesis, functions and role in tumor angiogenesis

T Annese, R Tamma, M De Giorgis, D Ribatti - Frontiers in oncology, 2020 - frontiersin.org
tumor initiation and progression are addressed. In particular, we describe the role of miRNA
in sprouting angiogenesis, … pathway, protein translation, and collagen formation. Instead, the …

[HTML][HTML] Reciprocal interplay between fibrillar collagens and collagen-binding integrins: implications in cancer progression and metastasis

I Bourgot, I Primac, T Louis, A Noël, E Maquoi - Frontiers in oncology, 2020 - frontiersin.org
… Several key biophysical parameters of type I collagen matrix play a role in cancer cell …
Stromal integrins, on the other hand, are implicated in processes such as tumor angiogenesis, …