IL-6 family cytokines: Key inflammatory mediators as biomarkers and potential therapeutic targets
N Unver, F McAllister - Cytokine & growth factor reviews, 2018 - Elsevier
… Screening of cytokines can serve to identify immunological … as diagnostic biomarker and
this cytokine has also been … as well as potential therapeutic targets for treatment of cervical …
this cytokine has also been … as well as potential therapeutic targets for treatment of cervical …
Potential therapeutic targets beyond cytokines and Janus kinases for autoimmune arthritis
CY Wu, HY Yang, JH Lai - Biochemical Pharmacology, 2023 - Elsevier
… serve as therapeutic targets [11]. To identify therapeutic targets beyond cytokines and JAKs
… We also propose and summarize potential novel therapeutic targets beyond those of current …
… We also propose and summarize potential novel therapeutic targets beyond those of current …
[HTML][HTML] Cytokine-defined B cell responses as therapeutic targets in multiple sclerosis
… of human cytokine-defined B … cytokine-defined B cells contribute to the peripheral immune
cascades that are thought to underlie MS relapses, and the impact of B cell-directed therapies …
cascades that are thought to underlie MS relapses, and the impact of B cell-directed therapies …
Current and emerging therapeutic targets for IBD
MF Neurath - Nature Reviews Gastroenterology & Hepatology, 2017 - nature.com
… blockers (such as ustekinumab and JAK inhibitors) suppressing cytokine signalling are
probably a new addition to our future clinical armamentarium for patients with IBD …
probably a new addition to our future clinical armamentarium for patients with IBD …
[HTML][HTML] Cytokine-modulating strategies and newer cytokine targets for arthritis therapy
SH Venkatesha, S Dudics, B Acharya… - International journal of …, 2014 - mdpi.com
… , are the prime therapeutic targets for this debilitating … cytokines are already in the clinic and
additional new ones are in clinical/preclinical trials. Gene therapy targeting these cytokines is …
additional new ones are in clinical/preclinical trials. Gene therapy targeting these cytokines is …
[HTML][HTML] Multiple roles for cytokines in atopic dermatitis: from pathogenic mediators to endotype-specific biomarkers to therapeutic targets
… cytokines in the pathogenesis of AD, considering patients with various clinical AD phenotypes.
Moreover, we describe the cytokine … the presence of multiple cytokine axes involved in the …
Moreover, we describe the cytokine … the presence of multiple cytokine axes involved in the …
Th17 cytokines: novel potential therapeutic targets for COPD pathogenesis and exacerbations
O Le Rouzic, M Pichavant, E Frealle… - European …, 2017 - Eur Respiratory Soc
… crucial to guide future therapeutics. As T-helper cell (Th)17 cytokines play a key role in driving
mucosal immune responses, this review focuses on the role of Th17 cytokines, interleukin (…
mucosal immune responses, this review focuses on the role of Th17 cytokines, interleukin (…
Therapeutic targeting of Toll-like receptors for infectious and inflammatory diseases and cancer
… in this review, to justify them as therapeutic targets. These validation criteria are standard— …
inflammatory cytokines such as TNF and IL-6, which have proven to be excellent targets for …
inflammatory cytokines such as TNF and IL-6, which have proven to be excellent targets for …
Cytokines as therapeutic targets in primary Sjögren syndrome
S Retamozo, A Flores-Chavez… - … & therapeutics, 2018 - Elsevier
… potential pharmacotherapeutic options targeting the main cytokine families involved in the
etiopathogenesis of primary SjS and analyzes potential insights for developing new therapies. …
etiopathogenesis of primary SjS and analyzes potential insights for developing new therapies. …
Investigating the Potential Mechanisms and Therapeutic Targets of Inflammatory Cytokines in Post-stroke Depression
Y Zhang, Y Yang, H Li, Q Feng, W Ge, X Xu - Molecular Neurobiology, 2024 - Springer
… of cytokines in stroke and PSD while identifying their potential as specific therapeutic targets
… regulating inflammatory cytokine expression and anti-inflammatory cytokines like interleukin-…
… regulating inflammatory cytokine expression and anti-inflammatory cytokines like interleukin-…