Quantitative lung morphology in newborn mammals

D Bartlett Jr, JG Areson - Respiration physiology, 1977 - Elsevier
We have examined the lungs of eleven species of newborn mammals by quantitative
morphometric techniques and related the findings to body weight (BW) and O 2 …

Lung growth and alveolar multiplication.

WM Thurlbeck - Pathobiology annual, 1975 - europepmc.org
As the lung grows in volume from infancy to adult life, considerable amounts of tissue are
added to the lung, mostly as a result of alveolar multiplication. Species differences may exist …

A morphometric quantitation of developmental changes in elastic fibers in rat lung parenchyma: variability with lung region and postnatal age

MC Bruce, PY Lo - The Journal of laboratory and clinical …, 1991 - translationalres.com
Elastin has long been thought to play a pivotal role in alveolar septal development by
providing the structural framework around which new alveoli develop in the immature lung …

The effect of age on lung structure in male BALB/cNNia inbred mice

M Kawakami, JL Paul… - American journal of …, 1984 - Wiley Online Library
Morphometric examination using light, scanning electron, and transmission electron
microscopy was performed on the lungs from 32 inbred male BALB/cNNia mice between 38 …

Is length an appropriate estimator to characterize pulmonary alveolar capillaries? A critical evaluation in the human lung

C Mühlfeld, ER Weibel, U Hahn… - … Record: Advances in …, 2010 - Wiley Online Library
Stereological estimations of total capillary length have been used to characterize changes in
the alveolar capillary network (ACN) during developmental processes or pathophysiological …

Formation of alveoli in rats: postnatal effect of prenatal dexamethasone

GD Massaro, D Massaro - American Journal of Physiology …, 1992 - journals.physiology.org
We administered a glucocorticosteroid (dexamethasone) or its diluent to pregnant rats on
gestation days 17, 18, and 19. In male offspring we determined the lung's gas exchange …

Morphometric analysis of fetal rat lung development

M Moschopulos, PH Burri - The Anatomical Record, 1993 - Wiley Online Library
Applying the zone concept described previously, we quantitatively analyzed fetal rat lung
development. The zone concept allowed us to coherently define reference spaces in the …

Morphometric assessment of pulmonary toxicity in the rodent lung

DM Hyde, DJ Magliano, CG Plopper - Toxicologic pathology, 1991 - journals.sagepub.com
An overview of the epithelial and interstitial composition of rat respiratory airways shows
complexity and variability. Airway epithelium varies in 1) different airway levels; 2) the types …

Estimating structural alterations in animal models of lung emphysema. Is there a gold standard?

M Ochs - Annals of Anatomy-Anatomischer Anzeiger, 2014 - Elsevier
Chronic obstructive pulmonary disease (COPD) is one of the most common lung diseases.
The major component of COPD, which affects the gas-exchanging parenchyma of the lung …

Postnatal lung function in the developing rat

I Bolle, G Eder, S Takenaka… - Journal of Applied …, 2008 - journals.physiology.org
Little is known about lung function during early stages of postnatal maturation, although the
complex structural changes associated with developing rat lung are well studied. We …