Mendel's Law of equal segregation states that each of the two alleles in a diploid organism
has an equal probability of being transmitted into... Meiotic drive occurs when a selfish …

Genetic elements that cheat Mendelian segregation by biasing transmission in their favor
gain a significant fitness benefit. Several examples of sex-ratio meiotic drive, where one sex …

Mutations with conflicting fitness effects in males and females accumulate in sexual
populations, reducing their adaptive capacity. 1, 2 Although quantitative genetic studies …

Segregation Distorter (SD) is an autosomal meiotic drive gene complex found worldwide in
natural populations of Drosophila melanogaster. During spermatogenesis, SD induces …

SR chromosomes are the best-known case of sex chromosome meiotic drive. These X
chromosomes cause the production of female-biased progenies in several Drosophila …

Publisher Summary Some selfish genetic elements in eukaryotic genomes have been
harnessed to perform essential functions for their hosts, whereas others have gained …

The recent evolutionary history of the Y chromosome in Drosophila simulans, a worldwide
species of Afrotropical origin, is closely linked to that of X-linked meiotic drivers (Paris …

A large portion of the annotated genes in Drosophila melanogaster show sex-biased
expression, indicating that sex and reproduction-related genes (SRR genes) represent an …

Selfish genetic elements use a myriad of mechanisms to drive their inheritance and ensure
their survival into the next generation, often at a fitness cost to its host. 1, 2 Although the …

Y chromosomes are typically viewed as genetic wastelands with few intact genes. Recent
genomic analyses in Drosophila, however, show that gene gain is prominent on young Y …