过去一年中添加的文章,按日期排序

[HTML][HTML] Fragment-based drug discovery and biological evaluation of novel cannabinol-based inhibitors of oxytosis/ferroptosis for neurological disorders

Z Liang, A Candib, D Soriano-Castell, W Fischer… - Redox Biology, 2024 - Elsevier
51 天前 - … is an emerging field of research owing to its pathophysiological relevance to a
wide range of neurological disorders, including Alzheimer's and Parkinson's diseases and …

Immunotherapy: An emerging treatment option for neurodegenerative diseases

A Mukherjee, S Biswas, I Roy - Drug Discovery Today, 2024 - Elsevier
51 天前 - … being realized for neurodegenerative diseases in advanced … immunotherapies in
Parkinson’s and Alzheimer’s diseases. … in clinical trials for Parkinson disease (not all trials of a …

Molecular Communication-Based Intelligent Dopamine Rate Modulator for Parkinson's Disease Treatment

OB Akan - arXiv e-prints, 2024 - ui.adsabs.harvard.edu
52 天前 - Parkinson's disease (PD) is a progressive neurodegenerative disease, and it is
caused by the loss of dopaminergic neurons in the basal ganglia (BG). Currently, there is no …

72nd annual meeting of the Italian society of physiology: new perspectives in physiological research

A Gerbino, G Tamma, F Conti, G Valenti - Frontiers in Physiology, 2024 - frontiersin.org
55 天前 - … array of topics that emerged from the rich texture of … diseases, notably Parkinson’s
disease (PD), where a repurposing strategy involving Type 2 Diabetes Mellitus (T2DM) drugs

Towards enabling precision medicine in Alzheimer's disease and Parkinson's disease

C Birkenbihl - 2024 - bonndoc.ulb.uni-bonn.de
59 天前 - … course of the disease. The emerging healthcare paradigm of precision medicine
aims to address these challenges by bringing the right drug to the right patient at the right time. …

Motor Complications in Parkinson's Disease: Results from 3343 Patients Followed for up to 12 Years

SE Gandhi, T Zerenner, A Nodehi… - Movement Disorders …, 2024 - Wiley Online Library
60 天前 - … Motor complications were more common among those with higher drug doses,
younger … ), with associations emerging 2–4 years post‐diagnosis. Higher Parkinson's GRS was …

Fragment-based drug discovery for disorders of the central nervous system: designing better drugs piece by piece

BWGL Chan, NB Lynch, W Tran, JM Joyce… - Frontiers in …, 2024 - frontiersin.org
66 天前 - … Fragment-based drug discovery (FBDD) has emerged as a powerful strategy to
confront the challenges faced by conventional drug development approaches, particularly in the …

Global Research Status and Trends in Pharmacogenomics: Bibliometric Analysis and Visualization of the Past 20 Years

G Zhang, J Liu, Z Wang, L Zou, Y Ding - Available at SSRN 4745871 - papers.ssrn.com
68 天前 - Background: Pharmacogenomics is now recognized as a valuable tool for guiding
personalized and precise treatments, minimizing adverse events, and enhancing drug

Spatial neurolipidomics—MALDI mass spectrometry imaging of lipids in brain pathologies

D Jha, K Blennow, H Zetterberg… - Journal of Mass …, 2024 - Wiley Online Library
74 天前 - … Understanding spatial lipid biology in nervous tissue is therefore a key and emerging
… MPTP-lesioned macaque brain tissue, a Parkinson's disease animal model. The lateral …

[PDF][PDF] HOT TOPICS

N de Lisboa - research.unl.pt
74 天前 - … form the cornerstone of Parkinson’s disease (PD) treatment. … Motor deficits gradually
emerged over four re-exposure … for individuals with Parkinson disease may unlock benefits…