[HTML][HTML] Targeted knockout of Mx in the DF-1 chicken fibroblast cell line impairs immune response against Newcastle disease virus

L Wang, Z Xue, J Wang, Y Jian, H Lu, H Ma, S Wang… - Poultry Science, 2023 - Elsevier
… In conclusion, Mx played an important role in antivirus … was extracted via genomic DAN
extraction kit (TransGen Biotech, … immune defense, and induced the expressions of IFN-α and …

Chicken melanoma differentiation-associated gene 5 (MDA5) recognizes infectious bursal disease virus infection and triggers MDA5-related innate immunity

CC Lee, CC Wu, TL Lin - Archives of virology, 2014 - Springer
… innate immune response in the chicken MDA5 (chMDA5) signaling pathway. … extraction,
respectively. IBDV RNA loads and mRNA expression levels of chicken MDA5, interferon-β (IFN-β…

Chicken TBK1 interacts with STING and is involved in IFN-β signaling regulation

Y Cheng, J Ma, Y Liu, Q Gao, Y Yan, H Wang… - … Immunology, 2017 - Elsevier
… chTBK1 mRNA was widely expressed in different tissues. … (B) The purified complex was
analyzed using liquid … -β dependent on its protein kinase activity. The subsequent mutation …

Cross-species genome-wide analysis reveals molecular and functional diversity of the unconventional interferon-ω subtype

LE Shields, J Jennings, Q Liu, J Lee, W Ma… - … in Immunology, 2019 - frontiersin.org
activity assays, we synthesized several porcine IFN peptides … IFN peptides were collected
and partially purified using two … to the surges of IFN genes in amphibians, chickens, bats, …

The different expression of immune-related cytokine genes in response to velogenic and lentogenic Newcastle disease viruses infection in chicken peripheral blood

WQ Liu, MX Tian, YP Wang, Y Zhao, NL Zou… - Molecular biology …, 2012 - Springer
… Total RNA extraction from the peripheral blood samples was … In this study, the expression of
IFN alpha reached its peak on 3 … -specific immunity still play its anti-virus role even in the late …

Exacerbated apoptosis of cells infected with infectious bursal disease virus upon exposure to interferon alpha

LL Cubas-Gaona, E Diaz-Beneitez, M Ciscar… - Journal of …, 2018 - Am Soc Microbiol
… , an exacerbated cytokine immune response and B cell depletion … 11 IFN treatment triggers
apoptosis of IBDV-infected chicken … to IFN-induced apoptosis, those transfected with purified

GATA3 inhibits viral infection by promoting microRNA-155 expression

J Li, A Haiyilati, L Zhou, J Chen, Y Wang, L Gao… - Journal of …, 2022 - Am Soc Microbiol
… as an antivirus transcription factor in host innate immuneactivities were normalized to the
Renilla luciferase activities … 10A), purified chicken IFN-β by affinity chromatography using …

Preparation and immunological activity of polysaccharides and their derivatives

F Chen, G Huang - International Journal of Biological Macromolecules, 2018 - Elsevier
… have many biological activities such as anti-virus, anti-tumor, immune … were used to treat
Newcastle disease virus in chickens. … interferon, IL-2 and other soluble immune activity medium. …

Interferon-beta, interferon-gamma and their fusion interferon of Siberian tigers (Panthera tigris altaica) in China are involved in positive-feedback regulation of …

M Mu, H Zhao, Y Wang, M Guo, X Nie, Y Liu… - … Comparative Immunology, 2021 - Elsevier
… extracted from blood with lymphocyte extraction kit (Solarbio, … animals IFN-β than between
PtIFN-β and that of poultry or … function, we detected their antivirus activities using cytopathic …

[HTML][HTML] Research progress on the mechanisms underlying poultry immune regulation by plant polysaccharides

RH Zhao, FX Yang, YC Bai, JY Zhao, M Hu… - Frontiers in Veterinary …, 2023 - frontiersin.org
… via water extraction and ethanol precipitation, and it has … activities, such as antioxidation,
immune regulation, antivirus… IL-2 and IFN-γ to mediate the immune response and enhance the …