Immune alterations and immunotherapy prospects in head and neck cancer

V Varilla, J Atienza, CA Dasanu - Expert opinion on biological …, 2013 - Taylor & Francis
… (wt) p53-derived epitopes are present as well Citation[48]. … of CD8 + T cells was shown to
increase with the tumor grade … replaced by a Pan–DR–epitope (PADRE) sequence, was shown …

Immune recognition of cancer-tumor antigens

P Robbins - Tumor Immunology. London: Taylor & Francis, 2002 - api.taylorfrancis.com
… peptide epitopes recognized by CD8+ tumor-reactive T cells … high precursor frequency of
T cells reactive with this epitope. … A wild type peptide, p53:187–197, was found to elicit an …

Increasing Patterns of Regulatory T Cells in the Peripheral Blood of Gynecological Cancer Patients

MH Jung, YM Kim, HO Yang, HY Song… - Journal of …, 2005 - journals.lww.com
… native CD138 epitope and heteroclitic XBP1 epitopes that … HLA-A2 positive patients using
HLA-A2 matched p53 derived … mice: MataHari (CD8 cells) and Marilyn (CD4 cells), specific …

Developing anti-p53/HLA-A* 0201 T-cell receptor mimic antibodies for cancer immunotherapy

I Trenevska - 2019 - ora.ox.ac.uk
wild type p53 rather than mutated p53 epitopes ............ 50 1.5 … Once at the cell surface, the
TCR of CD8+ T cells recognises … peptide by MHC-I can all affect the epitope density at the cell

[PDF][PDF] Immunization with a p53 synthetic long peptide vaccilile induces p53-specifiic immune responses in patients with ovarian cancer, a phase II trial

…, CJ Melief, SH van der Burg, T Daemen… - … for Ovarian Cancer, 2009 - research.rug.nl
… Mixes of SLP are likely to contain multiple HLA class I and II T-cell epitopesCD8+ T-cell
reactivity and this was not unexpected as the p53-specific CD8+ T-cell, but not the CD4+ T cell

[HTML][HTML] Prospects for immunotherapy as a novel therapeutic strategy against hepatocellular carcinoma

Y Akazawa, T Suzuki, T Yoshikawa, S Mizuno… - World Journal of Meta …, 2019 - wjgnet.com
Increased frequencies of CD8+ T lymphocytes recognizing wild-type p53-derived epitopes
in peripheral blood correlate with presence of epitope loss tumor variants in patients with …

[HTML][HTML] The good and the bad of T cell cross-reactivity: challenges and opportunities for novel therapeutics in autoimmunity and cancer

C Gouttefangeas, R Klein, A Maia - Frontiers in Immunology, 2023 - frontiersin.org
… from CD8 + T cells), leads to inflammation and tissue damage with … CeD patients, processes
gluten to T cell reactive epitopes … when mice were injected with p53-derived peptides. In this …

p53: from fundamental biology to clinical applications in cancer

M Capuozzo, M Santorsola, M Bocchetti, F Perri… - Biology, 2022 - mdpi.com
… , T cells armed against wild-type p53 epitopes recognize … -chain T-cell receptor domain that
recognizes a peptide epitope … CD4+ and CD8+ T cells recognizing a p53 peptide repertoire …

Expression of the 5T4 Oncofoetal Antigen in Renal Cell Carcinoma: A Potential Target for T-Cell Based Immunotherapy

RW Griffiths, A Dangoor, DE Gilham… - Journal of …, 2005 - journals.lww.com
… native CD138 epitope and heteroclitic XBP1 epitopes that … HLA-A2 positive patients using
HLA-A2 matched p53 derived … mice: MataHari (CD8 cells) and Marilyn (CD4 cells), specific …

Identification of Cytotoxic T Lymphocyte Epitopes Derived From the Cancer/Testis Antigen, TAG

SJ Adair, TM Carr, KT Hogan - Journal of Immunotherapy, 2005 - journals.lww.com
… native CD138 epitope and heteroclitic XBP1 epitopes that … HLA-A2 positive patients using
HLA-A2 matched p53 derived … mice: MataHari (CD8 cells) and Marilyn (CD4 cells), specific …