… on neuronal function recovery after traumatic brain damage. … , the ability to reduce cerebral
edema, reducing inflammatory cascade, … and neuroinflammation in young rats. These results …

… therapies for traumatic brain injury (TBI) depend on successful delivery, … neural stem cells
(LMNSC008) demonstrate an inherent tropism to injury sites after intranasal (IN) administration…

… nerve growth factor (NGF), brain-derived neurotrophic factor (… following TBI in a rat model.
Unfortunately, the poor blood–… demonstrated to attenuate aquaporin-4 induced edema, 202 …

… Intranasal neuropeptide Y attenuates PTSD-like symptoms in … nerve growth factor was delivered
to the rat brain 30–45 min … and growth factors have been administered by the nasal route …

… to reduced cerebral infarction and better outcomes after neural insult. One study found that
intranasal administration of nerve growth factor after TBI attenuated the edema response and …

… treatment of Alzheimer's disease (AD) using nasal route. Development of various material-…
drug delivery systems possessing the ability to follow intranasal (IN) route for brain targeting, …

… and further vasogenic edema, especially MMP-9. The result of a recent study shows that,
in MMP-9 knock-out mice, BBB disruption was attenuated compared with the wild type …

… , intranasal administration of the 26.5 kDa recombinant human nerve growth factor in rats …
higher (depending on the brain region) than concentrations observed following intravenous …

… may not be suitable for attenuating TBI pathologies. Secondly, … are growth factors that promote
neuronal growth and survival … maze, one week after injury in rat and mouse models of TBI […

… Activation of transcription factor, nuclear factor kappa B (NF-κB), has … in rats at 1 h, 2 h, 24
h, 48 h, 1 week, 2 weeks, 1 month, 2 months, 6 months, and 1 year following brain injury in rats. …