Acute brain injury and nanomedicine: sex as a biological variable

A Simmons, O Mihalek, HA Bimonte Nelson… - Frontiers in …, 2024 - frontiersin.org
… , absorption is initiated in the gastrointestinal tract, where sex … vascular pericyte migration
through estrogen receptors ER-ɑ … effects on serum biochemistry for female versus male rats …

Matrix Metalloproteinase-9 inhibitors as therapeutic drugs for traumatic brain injury

A Sunny, RR James, SR Menon, S Rayaroth… - Neurochemistry …, 2023 - Elsevier
… Also, a positive correlation between serum MMP-9 levels and … , doxycycline-induced gut
microbiota modifications might … which are mediated by the estrogen receptors ER- and ER-β. …

[HTML][HTML] Never fear, the gut bacteria are here: Estrogen and gut microbiome-brain axis interactions in fear extinction

LY Maeng, A Beumer - International Journal of Psychophysiology, 2023 - Elsevier
… specific estrogen receptors in both male and female mice as well … Gut microbiota can and
do modulate serum, fecal and … of gut microbial activity such as neurotransmitters, cytokines, …

[HTML][HTML] Neuroendocrine pathogenesis of perimenopausal depression

Y Han, S Gu, Y Li, X Qian, F Wang, JH Huang - Frontiers in Psychiatry, 2023 - frontiersin.org
estrogen receptor, interaction between HPA axis and HPG axis, and micro-organism-brain
gutbrain damage, mainly the hippocampus damage that leads to neurocognitive impairment. …

[HTML][HTML] Why Is Multiple Sclerosis More Frequent in Women? Role of the Immune System and of Oral and Gut Microbiota

M D'Anca, FR Buccellato, GM Tartaglia, M Del Fabbro… - Applied Sciences, 2023 - mdpi.com
… expression of estrogen receptors on different immune cells … cytokines, such as IFNγ and
IL-17, with a detrimental effect for … and changes in serum metabolic profile [42]. Members of the …

[HTML][HTML] From menopause to neurodegeneration—molecular basis and potential therapy

YJ Cheng, CH Lin, HY Lane - International journal of molecular sciences, 2021 - mdpi.com
… Through binding to estrogen receptor (ER), 17β-estradiolSince estrogen can affect the
GI tract and the gutbrain axis … on head injury [223], and the changes in sex hormones at …

[HTML][HTML] 17β-Estradiol, a potential ally to alleviate SARS-CoV-2 infection

AC Breithaupt-Faloppa, CJ Correia, CM Prado… - Clinics, 2020 - SciELO Brasil
… the sex differences and the role of estradiol in modulating the … These cytokines are also
increased in both the serum and … Estradiol receptors agonists induced effects in rat intestinal

Making migraine easier to stomach: the role of the gutbrain− immune axis in headache disorders

M Sgro, J Ray, E Foster… - European Journal of …, 2023 - Wiley Online Library
… of gut commensal bacteria within serum, does fluctuate in … Estrogen receptor beta is essential
for sprouting of nociceptive … between traumatic brain injury, inflammation, and disease. …

The interplay of sex steroids, the immune response, and the intestinal microbiota

F Pace, PI Watnick - Trends in Microbiology, 2021 - cell.com
… , the composition of gut microbiota plays an important role in … estrogen receptor GPER-1
and nuclear estrogen receptors α (… (TLRs) and proinflammatory cytokines but also suppresses …

Sex Dimorphism in Pain Threshold and Neuroinflammatory Response: The Protective Effect of Female Sexual Hormones on Behavior and Seizures in an Allergic …

M Elahi, Z Ebrahim Soltani, A Afrooghe… - Journal of Neuroimmune …, 2024 - Springer
… The blood samples were collected from abdominal aorta by … analyze the levels of IgE in the
serum. The protein levels of IL-… Sex hormones and estrogen receptor (ER) may influence NF-…