Regulation of epithelial sodium channel expression by oestradiol and progestogen in alveolar epithelial cells

L Luo, J Deng, D Wang, J He, W Deng - Respiratory Physiology & …, 2015 - Elsevier
Oestrogen (E) and progestogen (P) exert regulatory effects on the epithelial Na+ channel
(ENaC) in the kidneys and the colon. However, the effects of E and P on the ENaC and on …

Lung epithelial ion transport in neonatal lung disease

O Pitkänen - Neonatology, 2001 - karger.com
Lung epithelial ion transport promotes salt and water movement across the fetal and
neonatal lung epithelium. The mechanism is dependent on basolateral membrane Na-K …

Induction of epithelial sodium channel (ENaC) expression and sodium transport in distal lung epithelia by oxygen

B Rafli, AK Tanswell, O Pitkänen… - Current topics in …, 1999 - Elsevier
Publisher Summary This chapter discusses a study on induction of epithelial sodium
channel (ENaC) expression and sodium transport in distal lung epithelia by oxygen. The …

Na+-K+-ATPase gene regulation by glucocorticoids in a fetal lung epithelial cell line

S Chalaka, DH Ingbar, R Sharma… - American Journal of …, 1999 - journals.physiology.org
The Na+ pump, Na+-K+-ATPase, along with the Na+ channel is essential for the removal of
alveolar solute and fluid perinatally. Because Na+-pump mRNA and activity increase before …

Modification of biophysical properties of lung epithelial Na+ channels by dexamethasone

A Lazrak, A Samanta, K Venetsanou… - … of Physiology-Cell …, 2000 - journals.physiology.org
There is considerable interest in identifying the basic mechanisms by which dexamethasone
alters ion transport across the adult alveolar epithelium. Herein, we incubated synchronized …

A glucocorticoid‐induced Na+ conductance in human airway epithelial cells identified by perforated patch recording

MT Clunes, AG Butt, SM Wilson - The Journal of Physiology, 2004 - Wiley Online Library
The perforated patch recording technique was used to investigate the effects of
dexamethasone (0.2 μm, 24–30 h), a synthetic glucocorticoid, on membrane conductance in …

The influence of mode of delivery, hormonal status and postnatal O2 environment on epithelial sodium channel (ENaC) expression in perinatal guinea‐pig lung

DL Baines, HG Folkesson, A Norlin… - The Journal of …, 2000 - Wiley Online Library
We have studied factors that potentially modulate the expression of mRNA coding for
subunits of the amiloride‐sensitive sodium channel, αENaC and βENaC, in lungs of …

Catecholamine regulation of amiloride-sensitive Na+ transport in the fetal rat alveolar epithelium

Y Marunaka, N Niisato - Current topics in membranes, 1999 - Elsevier
Publisher Summary The chapter presents a study on catecholamine regulation of amiloride-
sensitive sodium ion (Na+) transport in the fetal rat alveolar epithelium. The chapter …

Expression of the epithelial sodium channel in airway epithelium of newborn infants depends on gestational age

O Helve, C Janér, O Pitkänen, S Andersson - Pediatrics, 2007 - publications.aap.org
OBJECTIVE. In the newborn infant, removal of fetal lung liquid from the airways depends on
ion transport through the airway epithelium. The epithelial sodium channel is considered …

Hormonal modulation of Na+ transport in rat fetal distal lung epithelial cells

SJ Ramminger, SK Inglis, RE Olver… - The Journal of …, 2002 - Wiley Online Library
Isolated rat fetal distal lung epithelial (FDLE) cells were cultured (≈ 48 h) on permeable
supports in medium devoid of hormones and growth factors whilst PO2 was maintained at …