Abstract Monocyte chemoattractant protein-1 (MCP-1) is a chemotactic cytokine that can
bind to its receptor cysteine–cysteine chemokine receptor 2 (CCR2) and plays an important …

We investigated whether blocking of monocyte chemoattractant-1 (MCP-1) function would
inhibit recruitment of tumor-associated macrophages (TAMs) and prevent tumor …

Infiltration of leukocytes is one of the hallmarks of the inflammatory response. Among the
leukocyte populations, neutrophils are the first to infiltrate, followed by monocytes and …

Chemokines with their network play an important role in cancer growth, metastasis, and host-
tumor interactions. Of many chemokines, CC motif chemokine ligand 24 (CCL24) has been …

CC chemokine receptor type 7 (CCR7) has been implicated in lymph node metastasis of
various cancers. Previous studies have revealed that epithelial‑mesenchymal transition …

A neoplastic tumor consists of cancer cells that interact with each other and non-cancerous
cells that support the development of the cancer. One such cell are tumor-associated …

CCL18 is a chemokine that is primarily expressed in monocytes, macrophages and
immature dendritic cells and plays a crucial role in immune and inflammation responses …

Metastasis is one of the primary causes for high mortality in patients with squamous cell
carcinoma of the head and neck (SCCHN). Our previous study showed that chemokine (C‐C …

Pancreatic cancer is an aggressive malignancy with a high metastatic potential that results
in a high mortality rate worldwide. Although macrophages have the potential to kill tumor …

Monocyte chemoattractant protein-1 (MCP-1, CCL2) is produced by many different types of
cells. In the current investigation, the effect of tumor-derived CCL2 on macrophages was …