Evaluating the anti-neuropathic effects of naringin-loaded chitosan nanocarriers in a murine model of constriction injury

M Safari, S Fakhri, H Maleki… - Journal of Bioactive …, 2024 - journals.sagepub.com
… ameliorated hyperalgesia and cold allodynia. In addition, the … neuropathic pain complications
related to sciatic nerve injury. … was evaluated using a 6-grade scoring system. The scoring …

The Novel Role of GPR183-Oxysterol Signaling in Chronic Pain

K Braden - 2022 - search.proquest.com
Chronic pathological pain is characterized by allodynia, when a … how GPR183 levels change
on different immune cell types … associated with neuropathic pain development, we used …

[PDF][PDF] Mechanisms and therapeutic relevance of neuro-immune communication

SS Chavan, VA Pavlov, KJ Tracey - Immunity, 2017 - cell.com
Peripheral immune cell activation with the release of cytokines and … Therefore,
catecholaminergic potentiation of the tissue-… of vagus nerve stimulation, and the adoptive transfer

[HTML][HTML] Stem cells and pain

MDV da Silva, M Piva… - … Journal of Stem Cells, 2023 - ncbi.nlm.nih.gov
… The immune system and nervous system are responsible for … and mechanical allodynia,
with the potentiated effects after … neuropathic pain behaviors in a rat model with L5 spinal …

Loss of μ opioid receptor signaling in nociceptors, but not microglia, abrogates morphine tolerance without disrupting analgesia

G Corder, VL Tawfik, D Wang, EI Sypek, SA Low… - Nature medicine, 2017 - nature.com
… can be combined with peripheral MOR antagonists to limit … -induced nociceptor maladaptive
potentiation over CNS analgesic … As opposed to the standard hot-plate test, we scored all …

Anti-allodynic effect of mangiferin in rats with chronic post-ischemia pain: a model of complex regional pain syndrome type I

BB Garrido-Suárez, G Garrido… - Frontiers in …, 2018 - frontiersin.org
… vessels, and immune cells leading to vasoconstriction, further … and allodynia in traumatic
models of neuropathic pain, also … long-term potentiation in the spinal dorsal horn via NF-κB in …

Targeting neuropathic pain: pathobiology, current treatment and peptidomimetics as a new therapeutic opportunity

MC Caroleo, A Brizzi, M De Rosa… - Current Medicinal …, 2020 - ingentaconnect.com
… or allodynia originating from central or peripheral nerve injuries. … of immune cells from periphery
into this anatomical site after … antagonists can potentiate opioid induced cell signaling via …

[图书][B] Diversity of microglial transcriptional responses during opioid exposure and neuropathic pain

EI Sypek - 2019 - search.proquest.com
… complement system is a key effector of the immune system, a … nerve, we next utilized a third
allodynia-inducing peripheral … Inhibiting proinflammatory cytokines potentiated analgesia and …

The role of regulatory T cells and interleukin-35 in pain associated with an animal model of multiple sclerosis

S Duffy - 2018 - unsworks.unsw.edu.au
… (ix) Involvement of regulatory T cells in neuropathic pain … in animal models of MS demonstrating
that adoptive transfer of … various immune cells of both arms of the innate and adaptive …

Lactoferrin and its potential impact for the relief of pain: A preclinical approach

B Godínez-Chaparro, F Guzmán-Mejía… - Pharmaceuticals, 2021 - mdpi.com
models of neuropathic pain, the lesion of the central or peripheral nervous system is able
to develop allodynia … , and a subeffective dose of bLf potentiated the morphine-induced anti-…