[HTML][HTML] NAD+ metabolism in peripheral neuropathic pain

Y Dai, J Lin, J Ren, B Zhu, C Wu, L Yu - Neurochemistry International, 2022 - Elsevier
… endothelial damage, leading to reduced nerve blood supply and … supply, and alleviate
hyperalgesia and allodynia. However, the … transcription factor A; TNF-α, tumor necrosis factor-α. …

Pathogenesis of paclitaxel-induced peripheral neuropathy: A current review of in vitro and in vivo findings using rodent and human model systems

NP Staff, JC Fehrenbacher, M Caillaud, MI Damaj… - Experimental …, 2020 - Elsevier
… conserved PIPN genes in animal models and patients, which … Many patients experience
allodynia, so that normal stimuli … In summary, neuronal cultures provide a reduced system to …

[HTML][HTML] Neurological complications of conventional and novel anticancer treatments

P Alberti, A Salvalaggio, AA Argyriou, J Bruna… - Cancers, 2022 - mdpi.com
… schedules have contributed to reduce CIPN associated with … , as etanercept (tumor necrosis
factor-α inhibition), ruloxitinib … of hippocampal neurogenesis in rat models. However, few …

Neuropathic pain: mechanisms, sex differences, and potential therapies for a global problem

S Ghazisaeidi, MM Muley… - Annual Review of …, 2023 - annualreviews.org
… options that help reduce the global burden of suffering. … , but was male specific for
bortezomib-induced hypersensitivity (65). … For example, SNI, an animal model utilized to study …

Neuroprotective effect of baicalein against oxaliplatin-induced peripheral neuropathy: Impact on oxidative stress, neuro-inflammation and WNT/β-catenin signaling

S Jugait, A Areti, K Nellaiappan, P Narwani… - Molecular …, 2022 - Springer
… nerve sections were incubated with primary antibodies WNT5b (Novus biological, USA, … )
and decreased score of allodynia (cold allodynia) in oxaliplatin group … Tumor necrosis factor α

Normalization of neuroinflammation: A new strategy for treatment of persistent pain and memory/emotional deficits in chronic pain

XG Liu - Journal of Inflammation Research, 2022 - Taylor & Francis
… feature of chronic pain in animal models and supplement Mg 2+ … disease, manifested
as allodynia (decrease in pain threshold), … 8 and 30 kDa, including tumor necrosis factor (TNF-α), …

[HTML][HTML] T cells as an emerging target for chronic pain therapy

G Laumet, J Ma, AJ Robison, S Kumari… - Frontiers in Molecular …, 2019 - frontiersin.org
… For example, Tumor Necrosis Factor α (TNFα) enhances the … that intrathecal anti-CD8 reduced
mechanical allodynia on … and CIPN as well as in animal models. These T cell profiles may …

Comparisons of the analgesic effect of different pulsed radiofrequency targets in SNI-induced neuropathic pain

Y Liang, S Zhong, H Wang, D Wu, Q Gong - NeuroReport, 2023 - journals.lww.com
… on the DRG reducing SNI-induced mechanical allodynia may be … application at different
locations in a rat model of SNI. ## P < … in pain regulatory genes [tumor necrosis factor-α (TNF-α), …

[HTML][HTML] Carbenoxolone has the potential to ameliorate acute incision pain in rats

S Dong, K Zhang, Y Shi - Molecular Medicine Reports, 2021 - spandidos-publications.com
decreased the levels of Px1 and Cx43, but also reduced the co… A rat model of acute IP was
established using the Brennan … C overnight with the following antibodies: Anti-Px1 antibody (1:…

[HTML][HTML] Platelets and the role of P2X receptors in nociception, pain, neuronal toxicity and thromboinflammation

E Rawish, HF Langer - International Journal of Molecular Sciences, 2022 - mdpi.com
… Moreover, EAE was ameliorated by antibodies against GPIIb/… was shown to reduce tactile
allodynia after peripheral nerve … injury and a suppression of tumor necrosis factor α (TNFα) IL-…