Engineering principles for guiding spheroid function in the regeneration of bone, cartilage, and skin

MA Gionet-Gonzales, JK Leach - Biomedical Materials, 2018 - iopscience.iop.org
… by sustained release of transforming growth factor-beta1 (TGF-… bone and cartilage tissue
engineering and wound healing. … TGF-β to cells within the aggregate using gelatin microspheres

[图书][B] Controlled Presentation of Genetic Material Within Stem Cell Condensations for Regulation of Cell Behavior for Bone Tissue Engineering

A McMillan - 2018 - search.proquest.com
… of polymer microspheres with controlled degradation profiles … by engineering biomaterials
that are biodegradable and/or … oxygen observed in tissue engineered cartilage [141]. These …

… -doped calcium polyphosphate composite scaffolds containing vascular endothelial growth factor (VEGF)-loaded gelatin microspheres for treating glucocorticoid …

Y Luo, D Li, X Xie, PD Kang - Biomedical Materials, 2019 - iopscience.iop.org
… subchondral bone and articular cartilage of the femoral head (… Simultaneously, Gelatin is
non-toxic, biodegradable, and can … Scaffolds used in bone tissue engineering should be three-…

[HTML][HTML] Exquisite design of injectable hydrogels in cartilage repair

J Wu, Q Chen, C Deng, B Xu, Z Zhang, Y Yang, T Lu - Theranostics, 2020 - ncbi.nlm.nih.gov
… use as scaffolds in cartilage and bone tissue engineering. Due … Notably, as alginate microbeads
exhibit excellent stability … ), interleukin-1(IL-1), and transforming growth factor-β (TGF-β). …

[HTML][HTML] Combination of mesenchymal stem cells and bioactive molecules in hydrogels for osteoarthritis treatment

P Gonzalez-Fernandez, C Rodriguez-Nogales… - European Journal of …, 2022 - Elsevier
… soluble factors such as transforming growth factor β (TGF-β), … the biodegradability of a slowly
degradable chitosan hydrogel … Glucose was released from the microspheres steadily over …

Chondrogenic effect of cell-based scaffold of self-assembling peptides/PLGA-PLL loading the hTGFβ3 plasmid DNA

Q Pan, W Li, X Yuan, Y Rakhmanov, P Wang… - Journal of Materials …, 2016 - Springer
scaffold for cartilage repair and offer a strategy for tissue regeneration through the use of
tissue engineering… tried to use biodegradable hydrogels for the local and sustained delivery of …

Bone regeneration using gene-activated matrices

S D'Mello, K Atluri, SM Geary, L Hong, S Elangovan… - The AAPS journal, 2017 - Springer
… This review discusses tissue engineering strategies to … phase, growth factors such as
transforming growth factor-β (… the polymer particles or microspheres into porous scaffolds (81). The …

[HTML][HTML] Design of injectable materials to improve stem cell transplantation

LM Marquardt, SC Heilshorn - Current stem cell reports, 2016 - Springer
… modified the hydrogel by conjugating transforming growth factor-β (… tissue engineering, a
non-invasive, injectable cell carrier … were delivered using cell-protective alginate beads within …

Biomaterial-guided delivery of gene vectors for targeted articular cartilage repair

M Cucchiarini, H Madry - Nature Reviews Rheumatology, 2019 - nature.com
Tissue engineering approaches provide adapted scaffolding … a biodegradable solid matrix
or a hydrogel before delivery … seldom used), fibrin 121 and chitosan 122 . HA is also currently …

[HTML][HTML] Scaffold-based gene therapeutics for osteochondral tissue engineering

X Yan, YR Chen, YF Song, M Yang, J Ye… - Frontiers in …, 2020 - frontiersin.org
… provides a more precise, controlled, and sustained release … of tissue engineering bionics
can induce cartilage or the … Conversely, hydrolytically degradable synthetic polymers …