… Of these, the dopamine transporter (DAT) is a principal target … release, whereas the D2
autoreceptor attenuates release. … DAT-inhibitor cocaine produces the opposite effect by promoting …

… Alternatively, serotonin may act postsynaptically to dopamine neurons, attenuating the
effects of cocaine-induced increases of extracellular dopamine on a downstream component of …

… Our results reveal the intracellular mechanisms that mediate DAT endocytic … DAT targeting
to degradation. We next tested whether cocaine binding to DAT influenced either targeting to …

… ceftriaxone attenuated acute cocaine-induced dopaminergic … Effects of acute cocaine on
extracellular dopamine in the … (DAT and dopamine stores) for cocaine to target within the …

… of cocaine and amphetamine are primarily the result of a direct interaction of these compounds
with DAT leading to attenuated dopamine … for proper membrane targeting of DAT but …

… attenuate many of the behavioral effects of cocaine, alone they have no effect on cocaine …
antibodies that bind to cocaine in the circulating blood and extracellular fluid, slowing down the …

… transporter by GBR explains its ability to attenuate cocaine-induced increases in extracellular
DA and to suppress cocaine … the appropriate occupancy level to target. The present study …

… dopaminergic neurotransmission by removing extracellular … , we target a similar region in
DAT that we previously targeted in SERT… attenuated the effects of cocaine at the 30 μM cocaine …

… antagonists attenuate many behavioral effects of cocaine but … σRs and that a combined
target approach may have utility in … , the cocaine-induced increases in extracellular dopamine …

… of the dopamine transporter as an obligate target for these … effects of cocaine cannot be
attributed solely to dopamine … following activation of protein kinase C was attenuated by co-…