Inadequate antibiotic dosing in patients receiving sustained low efficiency dialysis

LA Keough, A Krauss, JQ Hudson - International journal of clinical …, 2018 - Springer
… Background Patients requiring SLED are often critically ill and/… antibiotic therapy for life-threatening
infections. Antibiotic … for meropenem and piperacillin/tazobactam in SLED patients

Towards the rational use of antibiotics: Utilising pharmacometric approaches to improve meropenem and piperacillin treatment in critically ill patients

FA Weinelt - 2023 - refubium.fu-berlin.de
… in treating infectious diseases, bacterial infections remain a … The selection of an appropriate
dosing regimen can be … by severe and life-threatening illnesses: critically ill patients require …

Meropenem pharmacokinetics and target attainment in critically ill patients are not affected by extracorporeal membrane oxygenation: a matched cohort analysis

M Gijsen, E Dreesen, P Annaert, J Nicolai, Y Debaveye… - Microorganisms, 2021 - mdpi.com
… High rates of nosocomial infections with multidrug resistant … The aim of the present study is
to investigate the effect of … to be more appropriate in ICU patients [45], was retained as renal

Drug dosing during continuous renal replacement therapies

AJ Thompson - The Journal of Pediatric Pharmacology and …, 2008 - meridian.allenpress.com
… Six critically ill adults with acute renal failure and life-threatening Candida infections
received … The authors conclude that meropenem 500 mg IV q 12 hr is appropriate to treat …

Population pharmacokinetics and probability of target attainment of meropenem in critically ill patients

F Mattioli, C Fucile, V Del Bono, V Marini… - European journal of …, 2016 - Springer
… risk of treatment failure especially when severe or life-threatening infections are diagnosed.
… an effective and appropriate antimicrobial chemotherapy, as demonstrated in cystic fibrosis …

Meropenem use and therapeutic drug monitoring in clinical practice: a literature review

NA Steffens, ES Zimmermann… - Journal of clinical …, 2021 - Wiley Online Library
… prescribed for the treatment of life-threatening infections. The … them were carried out with
critically ill patients, such as septic … an appropriate adjustment of the meropenem dosage based …

A brief ICU residents' guide: Pharmacotherapy, pharmacokinetic aspects and dose adjustments in critically ill adult patients admitted to ICU

P Ghasemiyeh, S Mohammadi-Samani… - … and Critical Care, 2021 - Elsevier
… and these errors could be potentially life-threatening and … of therapy using appropriate
medicine in optimum dosage … factor of infection in critically ill patients. The incidence of viral …

[HTML][HTML] Doripenem dosing recommendations for critically ill patients receiving continuous renal replacement therapy

MN Samtani, N Vaccaro, I Cirillo, GR Matzke… - International Scholarly …, 2012 - hindawi.com
… with acute kidney impairment, are to avert the life-threatening … suitable for the treatment of
infections due to less susceptible pathogens. … of meropenem during intermittent and continuous

External evaluation of population pharmacokinetic models to inform precision dosing of meropenem in critically ill patients

N Yang, J Wang, Y Xie, J Ding, C Wu, J Liu… - Frontiers in …, 2022 - frontiersin.org
… in the treatment of severe infections in critically ill patients due to … using the nonlinear
mixed-effects modeling tool NONMEM 7.3 (… , may not be appropriate for describing the …

Optimizing antimicrobial drug dosing in critically ill patients

P Póvoa, P Moniz, JG Pereira, L Coelho - Microorganisms, 2021 - mdpi.com
… also integrate the choice of appropriate dosing (Figure 1). … of empirical colistin versus
meropenem in late VAP occurring in … changes occur in infected critically ill patients that often lead …