[HTML][HTML] The contribution of microglia to neuroinflammation in Parkinson's disease
K Badanjak, S Fixemer, S Smajić, A Skupin… - International Journal of …, 2021 - mdpi.com
… of Parkinson’s disease (PD) is on the rise. In recent years, inflammatory processes have
emerged … and iPSC-derived models, newly emerging technologies, and the resulting potential of …
emerged … and iPSC-derived models, newly emerging technologies, and the resulting potential of …
[HTML][HTML] Signaling pathways in Parkinson's disease: molecular mechanisms and therapeutic interventions
X Dong-Chen, C Yong, X Yang, ST Chen-Yu… - Signal transduction and …, 2023 - nature.com
Parkinson’s disease (PD) is the second most common neurodegenerative disease worldwide,
and its treatment remains a big challenge. The pathogenesis of PD may be related to …
and its treatment remains a big challenge. The pathogenesis of PD may be related to …
Repurposing anti-diabetic drugs for the treatment of Parkinson's disease: rationale and clinical experience
T Foltynie, D Athauda - Progress in Brain Research, 2020 - Elsevier
… already emerging from clinical trials in which patients with PD have been exposed to agents
licensed for the treatment of T2DM, during which the severity of their Parkinson's disease …
licensed for the treatment of T2DM, during which the severity of their Parkinson's disease …
[HTML][HTML] Meta-analysis of the Parkinson's disease gut microbiome suggests alterations linked to intestinal inflammation
… microbiome suggests alterations linked to intestinal inflammation | npj Parkinson's Disease
… The gut microbiota is emerging as an important modulator of neurodegenerative diseases, …
… The gut microbiota is emerging as an important modulator of neurodegenerative diseases, …
Mitochondrial unfolded protein response: An emerging pathway in human diseases
L Zhu, Q Zhou, L He, L Chen - Free Radical Biology and Medicine, 2021 - Elsevier
… and Parkinson's disease. … disease, Parkinson's disease and Huntington's disease. Besides,
UPR mt is also involved in the occurrence and development of cancers and heart diseases. …
UPR mt is also involved in the occurrence and development of cancers and heart diseases. …
Emerging technologies for improved deep brain stimulation
… The most common surgical target for the treatment of Parkinson's disease is the subthalamic
nucleus, which contains ~250,000 neurons, depicted in blue, and is much denser in reality …
nucleus, which contains ~250,000 neurons, depicted in blue, and is much denser in reality …
Nanotechnology based drug delivery system: Current strategies and emerging therapeutic potential for medical science
… in the brain stem are characteristic features of Parkinson's disease (PD). Nanotube arrays
… in degenerative diseases such as Alzheimer's disease and Parkinson's disease, which …
… in degenerative diseases such as Alzheimer's disease and Parkinson's disease, which …
Nanoparticles for drug delivery in Parkinson's disease
J Baskin, JE Jeon, SJG Lewis - Journal of Neurology, 2021 - Springer
… However, gold nanoparticles are emerging with Phase II clinical trials underway for multiple
sclerosis, amyotrophic lateral sclerosis, and Parkinson’s disease, which will be discussed …
sclerosis, amyotrophic lateral sclerosis, and Parkinson’s disease, which will be discussed …
[HTML][HTML] Neuroprotective Properties of Green Tea (Camellia sinensis) in Parkinson's Disease: A Review
DS Malar, MI Prasanth, JM Brimson, R Sharika… - Molecules, 2020 - mdpi.com
… emerged, the study on the role of green tea and its constituents in counteracting a diverse
range of disease … This review mainly focusses on Parkinson’s disease (PD) and the molecular …
range of disease … This review mainly focusses on Parkinson’s disease (PD) and the molecular …
The current status of pharmacotherapy for the treatment of Parkinson's disease: transition from single-target to multitarget therapy
SL Cheong, S Federico, G Spalluto, KN Klotz… - Drug discovery today, 2019 - Elsevier
… The single-drug–single-target approach has long dominated the pharmaceutical industry
with many successful drugs emerging from such a strategy. However, many diseases remain …
with many successful drugs emerging from such a strategy. However, many diseases remain …