… extend the life span of the long-lived growth hormone receptor knockout (GHRKO) mutant
mice further … oxidative stress and insulin signaling as possible contributors to the increase in …

… (that is cool for mice), the diminutive long-lived GH-related mutants … signaling in the liver
[91]. Moreover, treating progeroid … To what extent bile acids can impact BAT and longevity is …

… and extend life-span and health-span by an integrated signaling … and regulate energy and
homeostasis of bile acids, glucose, lipid, … These long-lived dwarf mice share many phenotypic …

… with residence olize steroids, bile acids, fatty acids, arachidonates, and xenobiotics… longevity
depending on the level or type of activity of al., 2000). Long-lived Ames and Snell dwarf mice…

… critical signaling molecules that regulate metabolism, development, and homeostasis. Oxysterols,
bile acids (… in several long-lived mouse models, including calorie-restricted mice, Snell …

… long-lived models, eg signal transduction pathways found to be commonly regulated during
hibernation are also known to induce lifespan … identified in long-lived mice compared to the …

… longevity and metabolism regulated by germline signals in C… in long-lived Ames dwarf mice
and Little mice compared with … , which is a bile acid conjugate of cholic acid and taurine, is a …

… as the analyses of 5 long-lived mouse models, 22 natural … -1 signaling pathway has been
found to extend lifespan, first … liver of bats; the bile acid conjugation strategies among carnivores…

… increased longevity are more frequently observed in long-lived … ) mice also had decreases
in insulin-stimulated signaling … -I signaling after CR in wild-type mice and in ad libitum dwarf …

… of bacterially deprived (BD) worms, which are long-lived due … associated with longevity
interventions in mice have also … of bacterial degradation of bile acids by metformin may be linked …