[HTML][HTML] STING agonist inflames the pancreatic cancer immune microenvironment and reduces tumor burden in mouse models

W Jing, D McAllister, EP Vonderhaar, K Palen… - … for immunotherapy of …, 2019 - Springer
… by an immune suppressive stromal reaction that creates a … from freshly isolated mouse
bone marrow cells. Briefly, … the composition and phenotype of tumor-infiltrating myeloid cells. …

[HTML][HTML] … injection of CCL19-expressing mesenchymal stem cells augments the therapeutic efficacy of anti-PD-L1 antibody by promoting infiltration of immune cells

Y Iida, R Yoshikawa, A Murata, H Kotani… - … for immunotherapy of …, 2020 - ncbi.nlm.nih.gov
… be isolated from adult mouse bone marrow.3 Several studies … of tumor-infiltrating immune
cells, including T cells and DC, … In this study, we prepared immortalized murine MSC (iMSC) …

A chimeric GM-CSF/IL18 receptor to sustain CAR T-cell function

S Lange, LGL Sand, M Bell, SL Patil, D Langfitt… - Cancer discovery, 2021 - AACR
… positive cells for the majority of functional analyses, unless … IL12 production by tumor-infiltrating
lymphocytes in early-… Nontransduced T cells were prepared similarly, except that no …

[HTML][HTML] … using in vivo fluorine-19 magnetic resonance: pilot study in a patient with head and neck carcinoma receiving tumor-infiltrating lymphocytes labeled with …

ET Ahrens, BM Helfer, CF O'Hanlon… - … for immunotherapy of …, 2023 - ncbi.nlm.nih.gov
… in blood samples or from invasive bone marrow aspirates. In these … Cellular preparations
were assayed using a Miltenyi … in a solid tumor model in mice reported11 liver 19 F signals that …

[PDF][PDF] Type I interferon activates MHC class I-dressed CD11b+ conventional dendritic cells to promote protective anti-tumor CD8+ T cell immunity

E Duong, TB Fessenden, E Lutz, T Dinter, L Yim, S Blatt… - Immunity, 2022 - cell.com
bone marrow chimeras (ItgaxDTR BMCs), a model where all CD11c+ (encoded by Itgax) …
Implanting MC57-SIY cells into B2M À/À BMC mice and profiling the tumor-infiltrating DCs, we …

Overcoming stromal barriers to immuno-oncological responses via fibroblast activation protein-targeted therapy

WN Brennen, DL J Thorek, W Jiang, TE Krueger… - …, 2021 - Future Medicine
tumor-infiltrating FAP-positive cells to overcome stromal … or HUVEC endothelial cells were
prepared according to previously … by stromal cells with a low proliferative index in vivo in mice

[HTML][HTML] Deciphering CD4+ T cell specificity using novel MHC–TCR chimeric receptors

J Kisielow, FJ Obermair, M Kopf - Nature immunology, 2019 - nature.com
… by tumor-infiltrating lymphocytes efficiently protects mice from … presented by bone marrow
derived dendritic cells (BMDCs). … preparation, tumor biopsies were pooled from multiple mice, …

B7-H3×4-1BB bispecific antibody augments antitumor immunity by enhancing terminally differentiated CD8+ tumor-infiltrating lymphocytes

G You, Y Lee, YW Kang, HW Park, K Park, H Kim… - Science …, 2021 - science.org
… Also, they induce bone marrow (BM) failure, including defects in … Tumor cells and tumor-associated
endothelial and stromal cells … BM cells were prepared into single cells for analyzing …

[HTML][HTML] Intratumoral immune triads are required for adoptive T cell therapy-mediated elimination of solid tumors

G Espinosa-Carrasco, A Scrivo, P Zumbo, A Dave… - bioRxiv, 2023 - ncbi.nlm.nih.gov
… equal numbers of tumor-infiltrating CD8 and CD4 T cells. Strikingly… bone marrow (BM)
chimeras by transferring BM cells from … nodes and tumors and prepared for downstream analyses. …

[HTML][HTML] Relevance of immune cell and tumor microenvironment imaging in the new era of immunotherapy

F Galli, JV Aguilera, B Palermo, SN Markovic… - Journal of experimental …, 2020 - Springer
Tumor-infiltrating immune cells play a key role against cancer… cellular metabolism and
function of both stromal and immune … tumor vaccines prepared using patient-derived tumor cells