Matrine-family alkaloids: versatile precursors for bioactive modifications

X Cai, H Zhang, B Xie - Medicinal Chemistry, 2020 - ingentaconnect.com
… isolated from the roots of Sophora flavescens (Kushen) [6-8]. At present, matrine-family …
in the field of anti-inflammatory, antiviral, antitumor, antiparasitic and other activities have been …

Deciphering Alkaloid and Flavonoid Biosynthesis in Different Tissues of Sophora tonkinensis via Transcriptomics and Metabolomics

Y Liang, G Wei, X Liang, M Tang, H He, D Tang, Y Lin… - 2024 - researchsquare.com
… and biological activity of effective components of Sophora Tonkinensis 725 … Quinolizidine
alkaloids 753 from Sophora tonkinensis and their anti-inflammatory activities. Fitoterapia. 754 …

Characterisation and antimicrobial activity of Sophora alopecuroides L. var. alopecuroides alkaloid extracts

N Küçükboyaci, S Özkan, N Adigüzel… - Turkish Journal of …, 2011 - journals.tubitak.gov.tr
Sophora species are known to contain quinolizidine alkaloids (QAs) as their principal …
sedative, analgesic, antipyretic, anti-inflammatory, anti-tumour and notable antiviral activities (2-5). …

Progress of plant medicine derived extracts and alkaloids on modulating viral infections and inflammation

H Ti, Z Zhuang, Q Yu, S Wang - Drug design, development and …, 2021 - Taylor & Francis
… Citation41 Aloperine (1), a quinolizidine alkaloid with an … (75) was isolated from the rhizomes
of Sophora tonkinensis. … of alkaloids to treat lung infections involving anti-inflammatory or …

Alopecines A–E, five chloro-containing matrine-type alkaloids with immunosuppressive activities from the seeds of Sophora alopecuroides

XF Wang, Z Zhu, TT Hao, QQ Fang, K Jiang, SJ Qu… - Bioorganic …, 2020 - Elsevier
… Matrine-type quinolizidine alkaloids are the biomarker component for Sophora species, …
and show a variety of biological activities, such as antiviral, antitumor and anti-inflammatory

Discovery, Topo I inhibitory activity and mechanism evaluation of two novel cytisine-type alkaloid dimers from the seeds of Sophora alopecuroides L

C Meng, Y Wang, S Chen, M Li, C Yuan… - Bioorganic & Medicinal …, 2022 - Elsevier
… monomeric alkaloids, dimeric quinolizidine alkaloids are … new quinolizidine alkaloid dimer
showed better anti-inflammatory effects than matrine, proving that the pharmacological activity

[HTML][HTML] Integrated transcriptome and small RNA sequencing analyses reveal a drought stress response network in Sophora tonkinensis

Y Liang, K Wei, F Wei, S Qin, C Deng, Y Lin, M Li… - BMC Plant …, 2021 - Springer
tonkinensis have shown that quinolizidine alkaloids and flavonoids are the … tonkinensis,
acts as the main medicinal active ingredient and has been proven to have anti-inflammatory, …

Oxymatrine: A current overview of its health benefits

DQ Huan, NQ Hop, NT Son - Fitoterapia, 2023 - Elsevier
… condition because of its anti-inflammatory (downregulation of cytokine mRNA, and … analysis
of quinolizidine alkaloids and their biosynthetic precursor, lysine, in Sophora alopercuroides …

[HTML][HTML] Research progress on antibacterial activities and mechanisms of natural alkaloids: A review

Y Yan, X Li, C Zhang, L Lv, B Gao, M Li - Antibiotics, 2021 - mdpi.com
… into simple pyridine alkaloids, quinolizidine alkaloids, and indolizidine alkaloids [8]. These
… glycoside alkaloids were isolated from Sophora tonkinensis. Antibacterial activity screening …

Quinolizidine alkaloids from Sophora tonkinensis and their anti-inflammatory activities.

HLJ He LiJun, LJS Liu JunShan, LD Luo Ding… - 2019 - cabidigitallibrary.org
… potent anti-inflammatory activities according to in vitro and in vivo anti-inflammatory tests. …
(12) showed more potent in vitro anti-inflammatory activities, and 5α,14β-dihydroxymatrine (2), (…