[PDF][PDF] Cardiac stem cell therapy and the promise of heart regeneration
JC Garbern, RT Lee - Cell stem cell, 2013 - cell.com
… But as the enthusiasm for cardiac regeneration charges ahead toward clinical translation,
it is crucial for all investigators to maintain objectivity and seek new and complementary ap…
it is crucial for all investigators to maintain objectivity and seek new and complementary ap…
[HTML][HTML] Applications of miRNAs in cardiac development, disease progression and regeneration
… the miRNA dysregulation in congenital heart disease and the … precisely define the appropriate
treatment duration, dosage … be a step towards translating it into clinical therapy, but even …
treatment duration, dosage … be a step towards translating it into clinical therapy, but even …
Cell therapy for heart failure: a comprehensive overview of experimental and clinical studies, current challenges, and future directions
SK Sanganalmath, R Bolli - Circulation research, 2013 - Am Heart Assoc
… Few ideas in medicine have been translated from the … of stem cell therapies in patients with
cardiovascular disease. … of cell-based therapies and proceed toward clinical translation, a …
cardiovascular disease. … of cell-based therapies and proceed toward clinical translation, a …
Cardiopoietic stem cell therapy in heart failure: the C-CURE (Cardiopoietic stem Cell therapy in heart failURE) multicenter randomized trial with lineage-specified …
J Bartunek, A Behfar, D Dolatabadi… - Journal of the American …, 2013 - jacc.org
… D, E) Impact of cardiopoietic stem cell therapy (Cell Therapy) on left … Changes in LVEF are
plotted against changes in left … Clinical translation of cardiopoietic stem cell therapy, performed …
plotted against changes in left … Clinical translation of cardiopoietic stem cell therapy, performed …
Clinical applications of stem cells for the heart
KC Wollert, H Drexler - Circulation research, 2005 - Am Heart Assoc
… The field now is rapidly moving toward intermediate-size, … learned from the translation of
therapeutic angiogenesis into clinical … option for patients with cardiovascular disease. Outcome …
therapeutic angiogenesis into clinical … option for patients with cardiovascular disease. Outcome …
[PDF][PDF] Stem cell therapies in clinical trials: progress and challenges
A Trounson, C McDonald - Cell stem cell, 2015 - cell.com
… funding of translation and clinical stem cell trials for sustained … clinical progress toward
successful therapy for this disease. … the formation of teratomas in these children. These types of …
successful therapy for this disease. … the formation of teratomas in these children. These types of …
Guided cardiopoiesis enhances therapeutic benefit of bone marrow human mesenchymal stem cells in chronic myocardial infarction
A Behfar, S Yamada, R Crespo-Diaz, JJ Nesbitt… - Journal of the American …, 2010 - jacc.org
… hMSC were harvested from a coronary artery disease patient cohort. A recombinant cocktail
… , Abbott Park, Illinois) via nick translation followed by hybridization and denaturation. Frozen …
… , Abbott Park, Illinois) via nick translation followed by hybridization and denaturation. Frozen …
[HTML][HTML] Clinical trials for stem cell therapies
A Trounson, RG Thakar, G Lomax, D Gibbons - BMC medicine, 2011 - Springer
… in clinical parameters of disability will translate into long-term … immune rejection is moving
towards the clinic but concerns … disorder that affects male children. Preclinical trials showed …
towards the clinic but concerns … disorder that affects male children. Preclinical trials showed …
The war against heart failure: the Lancet lecture
E Braunwald - The Lancet, 2015 - thelancet.com
… therapy; many short, non-coding RNAs—ie, microRNAs (miRNAs)—block gene expression
and protein translation. … 1), valvular and congenital heart disease, hypertension, and many …
and protein translation. … 1), valvular and congenital heart disease, hypertension, and many …
Mesenchymal stem cells: progress toward promise
K Le Blanc, MF Pittenger - Cytotherapy, 2005 - Taylor & Francis
… For instance, MSCs increase the transcription and translation … mesenchymal cells engraft
and stimulate growth in children with osteogenesis imperfecta: implications for cell therapy of …
and stimulate growth in children with osteogenesis imperfecta: implications for cell therapy of …