Is there a role for blood purification therapies targeting cytokine storm syndrome in critically severe COVID-19 patients?
G Chen, Y Zhou, J Ma, P Xia, Y Qin, X Li - Renal failure, 2020 - Taylor & Francis
… , blood purification therapies have a potential role in the treatment of severe COVID-19
combined with AKI. Some new membrane technologies targeting cytokine removal may result in …
combined with AKI. Some new membrane technologies targeting cytokine removal may result in …
Therapeutic targeting of IL-6 trans-signaling
S Rose-John - Cytokine, 2021 - Elsevier
Interleukin-6 (IL-6) is a cytokine, which is involved in innate and acquired immunity, in
neural cell maintenance and in metabolism. IL-6 can be synthesized by many different cells …
neural cell maintenance and in metabolism. IL-6 can be synthesized by many different cells …
'Prototypical'proinflammatory cytokine (IL-1) in multiple sclerosis: role in pathogenesis and therapeutic targeting
A Musella, D Fresegna, FR Rizzo… - … Therapeutic Targets, 2020 - Taylor & Francis
… We will discuss why anti-IL-1 therapies in MS have been neglected to date. … are
potentially reversible and, therefore, represent attractive therapeutic targets for MS [Citation83]. …
potentially reversible and, therefore, represent attractive therapeutic targets for MS [Citation83]. …
Review on therapeutic targets for COVID-19: insights from cytokine storm
ML de Mélo Silva Júnior, LMA de Souza… - Postgraduate …, 2021 - academic.oup.com
… to a vicious cycle of inflammation (cytokine storm) and tissue damage. Some drugs have
been studied as therapeutic targets (block to viral entry or to cytokine storm) and are listed in the …
been studied as therapeutic targets (block to viral entry or to cytokine storm) and are listed in the …
The Role of Cytokines in Cutaneous T Cell Lymphoma: A Focus on the State of the Art and Possible Therapeutic Targets
A Guglielmo, C Zengarini, C Agostinelli, G Motta… - Cells, 2024 - mdpi.com
… , from the immunopathogenesis and cytokine dynamics centred around TNF-α and IFN-γ
to evolving therapeutic modalities. Including all the major known and studied cytokines in this …
to evolving therapeutic modalities. Including all the major known and studied cytokines in this …
Emerging role of the macrophage migration inhibitory factor family of cytokines in neuroblastoma. pathogenic effectors and novel therapeutic targets?
E Cavalli, R Ciurleo, MC Petralia, P Fagone, R Bella… - Molecules, 2020 - mdpi.com
… factor (MIF) is a pleiotropic cytokine that plays a key role in … cytokines in NB and suggest
that MIF and possibly DDT inhibitors may be promising novel prognostic and therapeutic targets …
that MIF and possibly DDT inhibitors may be promising novel prognostic and therapeutic targets …
Interleukin-1 and the inflammasome as therapeutic targets in cardiovascular disease
… role of the NLRP3 inflammasome and IL-1 cytokines in the formation, progression, and …
cytokines with the pathogenesis of cardiovascular diseases. The future will likely include targeted …
cytokines with the pathogenesis of cardiovascular diseases. The future will likely include targeted …
TH2 cytokines and associated transcription factors as therapeutic targets in asthma
Y Nakamura, M Hoshino - … Drug Targets-Inflammation & Allergy, 2005 - ingentaconnect.com
… This review focuses on the potential therapeutic utilities for agents that manipulate TH2
cytokines and associated transcription factors and discusses novel strategies for immune …
cytokines and associated transcription factors and discusses novel strategies for immune …
Cytokines as villains and potential therapeutic targets in thyroid-associated ophthalmopathy: From bench to bedside
… -cytokine therapy in TAO, evidence linking specific cytokines … targets of these cytokines as
well as their disruption by small molecules and monoclonal antibodies as potential therapies …
well as their disruption by small molecules and monoclonal antibodies as potential therapies …
[HTML][HTML] Innate type-2 cytokines: from immune regulation to therapeutic targets
HY Kim, D Jeong, JH Kim, DH Chung - Immune Network, 2024 - ncbi.nlm.nih.gov
… strategies, specifically the utilization of biologics targeting pivotal cytokines (IL-4, IL-5, and …
cytokines in orchestrating immune responses positions them as promising therapeutic targets. …
cytokines in orchestrating immune responses positions them as promising therapeutic targets. …