Immunological memory crucially depends on CD4 T cells. In contrast with B cells, we find no
decisive evidence that CD4 T cells are permanently altered by antigen stimulation. We …

An important attribute of the adaptive immune system is the ability to remember a prior
encounter with a pathogen; an ability termed immunological memory. Bigger, better, and …

Memory T cells that are specific for one virus can become activated during infection with an
unrelated heterologous virus, and might have roles in protective immunity and …

The generation of protective immunological memory is the basis of effective vaccination.
Two distinct types of CD4+ and CD8+ memory T cells have been identified recently: central …

Studies on immunologic memory in animal models and especially in the human system are
instrumental to identify mechanisms and correlates of protection necessary for vaccine …

After antigenic stimulation in the context of" danger signals," naive T cells embark on a
programmed, intense expansion phase to counteract the rapid proliferation of pathogens …

Immunological memory is one of the features that define the adaptive immune response: by
generating specific memory cells after infection or vaccination, the host provides itself with a …

Immunological memory equips our immune system to respond faster and more effectively
against reinfections. This acquired immunity was originally attributed to long‐lived, memory …

Generating long-lasting, protective CD8+ T-cell memory via vaccination is critical for
combating infectious diseases. Advances in the past year have provided many new insights …

There is debate over whether effective T‐cell mediated protection against a second
infection, or post‐vaccination, is better done by central memory cells or effector memory …