Interplay of polygenic liability with birth-related, somatic, and psychosocial factors in anorexia nervosa risk: a nationwide study
BackgroundAlthough several types of risk factors for anorexia nervosa (AN) have been
identified, including birth-related factors, somatic, and psychosocial risk factors, their …
identified, including birth-related factors, somatic, and psychosocial risk factors, their …
The role of leptin and cortisol in hyperactivity in patients with acute and weight-recovered anorexia nervosa
S Ehrlich, R Burghardt, N Schneider… - Progress in Neuro …, 2009 - Elsevier
INTRODUCTION: In food-restricted rats, leptin as well as corticotropin releasing factor
attenuate semistarvation-induced hyperactivity (SIH). Results from studies in patients with …
attenuate semistarvation-induced hyperactivity (SIH). Results from studies in patients with …
Polymorphisms in the leptin (rs7799039) gene are associated with an increased risk of excessive gestational weight gain but not with leptin concentration during …
MC Martins, J Trujillo, DR Farias, G Kac - Nutrition research, 2017 - Elsevier
Single nucleotide polymorphisms (SNPs) in leptin (LEP) and leptin receptor (LEPR) have
been shown to be linked to obesity-related metabolic markers and phenotype. Therefore, we …
been shown to be linked to obesity-related metabolic markers and phenotype. Therefore, we …
Higher leptin levels in Asian Indians than Creoles and Europids: a potential explanation for increased metabolic risk
M Lilja, O Rolandsson, JE Shaw, V Pauvaday… - International journal of …, 2010 - nature.com
Background and purpose: Leptin predicts cardiovascular diseases and type 2 diabetes,
diseases to which Asian Indians are highly susceptible. As a risk marker, leptin's intra …
diseases to which Asian Indians are highly susceptible. As a risk marker, leptin's intra …
[HTML][HTML] Leptin and body weight regulation in patients with anorexia nervosa before and during weight recovery1–2
V Haas, S Onur, T Paul, DO Nutzinger… - The American journal of …, 2005 - Elsevier
Background: Leptin has been considered a starvation hormone, but its role in malnourished
patients is unknown. Objective: We aimed to characterize the role of leptin in metabolic …
patients is unknown. Objective: We aimed to characterize the role of leptin in metabolic …
Leptin in anorexia nervosa
ED Eckert, C Pomeroy, N Raymond… - The Journal of …, 1998 - academic.oup.com
Serum leptin levels are low in untreated anorexia nervosa, but studies of the exact
relationship between leptin and body weight and the impact of refeeding in anorectics are …
relationship between leptin and body weight and the impact of refeeding in anorectics are …
Genetic studies of leptin concentrations implicate leptin in the regulation of early adiposity
Leptin influences food intake by informing the brain about the status of body fat stores. Rare
LEP mutations associated with congenital leptin deficiency cause severe early-onset obesity …
LEP mutations associated with congenital leptin deficiency cause severe early-onset obesity …
Leptin levels in patients with anorexia nervosa are reduced in the acute stage and elevated upon short-term weight restoration
J Hebebrand, WF Blum, N Barth, H Coners… - Molecular …, 1997 - nature.com
Circulating leptin concentrations are known to be low in acute anorexia nervosa (AN), which
is characterized by low weight, amenorrhea and specific psychopathological features. In this …
is characterized by low weight, amenorrhea and specific psychopathological features. In this …
Hypercaloric diets differing in fat composition have similar effects on serum leptin and weight gain in female subjects with anorexia nervosa
B Mauler, S Dubben, M Pawelzik, D Pawelzik… - Nutrition research, 2009 - Elsevier
Weight regain in subjects with anorexia nervosa is associated with an increase in serum
leptin concentrations that is hypothesized to impair full weight restoration. As diets rich in n-3 …
leptin concentrations that is hypothesized to impair full weight restoration. As diets rich in n-3 …
Leptin reduces hyperactivity in an animal model for anorexia nervosa via the ventral tegmental area
LAW Verhagen, MCM Luijendijk, RAH Adan - European …, 2011 - Elsevier
Hyperactivity in anorexia nervosa (AN) is associated with low plasma leptin levels and
negatively impacts on disease outcome. Using an animal model that mimics features of AN …
negatively impacts on disease outcome. Using an animal model that mimics features of AN …