Cervical cancer, version 2.2015

WJ Koh, BE Greer, NR Abu-Rustum, SM Apte… - Journal of the National …, 2015 - jnccn.org
The NCCN Guidelines for Cervical Cancer provide interdisciplinary recommendations for
treating cervical cancer. These NCCN Guidelines Insights summarize the NCCN Cervical …

Advances in cervical cancer pharmacotherapies

M Markman - Expert Review of Clinical Pharmacology, 2014 - Taylor & Francis
While widely employed in the management of cervical cancer, the overall utility of systemic
anti-neoplastic agents in this clinical setting is quite modest. Cisplatin, the single most …

Management of advanced or recurrent cervical cancer: chemotherapy and beyond

LM Elit, H Hirte - Expert review of anticancer therapy, 2014 - Taylor & Francis
Metastatic or recurrent cervical cancer has a survival duration of approximately 12 months.
Thus, we review the outcomes of chemotherapy and/or novel agents for women who present …

The impact of systemic therapy beyond first-line treatment for advanced cervical cancer

J McLachlan, S Boussios, A Okines, D Glaessgen… - Clinical oncology, 2017 - Elsevier
Aims Despite recent advances in the primary and secondary prevention of cervical cancer, a
significant number of women present with or develop metastatic disease. There is currently …

Bevacizumab for advanced cervical cancer: final overall survival and adverse event analysis of a randomised, controlled, open-label, phase 3 trial (Gynecologic …

KS Tewari, MW Sill, RT Penson, H Huang… - The Lancet, 2017 - thelancet.com
Summary Background On Aug 14, 2014, the US Food and Drug Administration approved the
antiangiogenesis drug bevacizumab for women with advanced cervical cancer on the basis …

Bevacizumab in advanced cervical cancer: issues and challenges for low-and middle-income countries

B Gyawali, M Iddawela - Journal of global oncology, 2017 - ascopubs.org
Bevacizumab became the first molecular antibody to show survival benefit in advanced
cervical cancer. In the GOG-0240 (Paclitaxel and Cisplatin or Topotecan With or Without …

Prospects of molecularly-targeted therapies for cervical cancer treatment

A Carlos de Freitas… - Current drug …, 2015 - ingentaconnect.com
Cervical cancer is the third most common cancer among women worldwide and is
responsible for 275.000 deaths each year. The development of cervical cancer has been …

Development of bevacizumab in advanced cervical cancer: pharmacodynamic modeling, survival impact and toxicology

RN Eskander, KS Tewari - Future Oncology, 2015 - Future Medicine
Historically, patients with metastatic, persistent or recurrent cervical cancer had limited
therapeutic options. Despite several Phase II/III clinical trials, the combination of cisplatin …

[HTML][HTML] Biology and treatment of cervical adenocarcinoma

S Takeuchi - Chinese Journal of Cancer Research, 2016 - ncbi.nlm.nih.gov
Uterine cervical adenocarcinoma (ADC) has been increasing in its prevalence world widely
despite the decrease of squamous cell carcinoma (SCC). It comprises nearly 20-25% of the …

Integrating chemotherapy in the management of cervical cancer: a critical appraisal

L Kumar, S Gupta - Oncology, 2016 - karger.com
The management of locally advanced cervix cancer has undergone a paradigm shift during
the last decade. Concurrent chemoradiation (CCRT)(with cisplatin alone or in combination) …