Neuroendocrinology of reward in anorexia nervosa and bulimia nervosa: beyond leptin and ghrelin
The pathophysiology of anorexia nervosa (AN) and bulimia nervosa (BN) are still poorly
understood, but psychobiological models have proposed a key role for disturbances in the …
understood, but psychobiological models have proposed a key role for disturbances in the …
Integrative analyses highlight functional regulatory variants associated with neuropsychiatric diseases
Noncoding variants of presumed regulatory function contribute to the heritability of
neuropsychiatric disease. A total of 2,221 noncoding variants connected to risk for ten …
neuropsychiatric disease. A total of 2,221 noncoding variants connected to risk for ten …
Genome-wide analyses of self-reported empathy: correlations with autism, schizophrenia, and anorexia nervosa
Empathy is the ability to recognize and respond to the emotional states of other individuals. It
is an important psychological process that facilitates navigating social interactions and …
is an important psychological process that facilitates navigating social interactions and …
The anorexia nervosa genetics initiative (ANGI): overview and methods
LM Thornton, MA Munn-Chernoff, JH Baker… - Contemporary Clinical …, 2018 - Elsevier
Background Genetic factors contribute to anorexia nervosa (AN); and the first genome-wide
significant locus has been identified. We describe methods and procedures for the Anorexia …
significant locus has been identified. We describe methods and procedures for the Anorexia …
Genetic correlations of psychiatric traits with body composition and glycemic traits are sex-and age-dependent
Body composition is often altered in psychiatric disorders. Using genome-wide common
genetic variation data, we calculate sex-specific genetic correlations amongst body fat%, fat …
genetic variation data, we calculate sex-specific genetic correlations amongst body fat%, fat …
AgRP neurons control compulsive exercise and survival in an activity-based anorexia model
MC Miletta, O Iyilikci, M Shanabrough… - Nature …, 2020 - nature.com
Hypothalamic agouti-related peptide (AgRP) and neuropeptide Y-expressing neurons have
a critical role in driving food intake, but also in modulating complex, non-feeding behaviours …
a critical role in driving food intake, but also in modulating complex, non-feeding behaviours …
Conceptualizing body dissatisfaction in eating disorders within a self-discrepancy framework: a review of evidence
EL Lantz, ME Gaspar, R DiTore, AD Piers… - Eating and Weight …, 2018 - Springer
Body dissatisfaction, the negative subjective evaluation of one's body, is associated with
many negative psychological and physical health consequences. One conceptualization of …
many negative psychological and physical health consequences. One conceptualization of …
Epigenetics in eating disorders: a systematic review
Eating disorders are complex heritable conditions influenced by both genetic and
environmental factors. Given the progress of genomic discovery in anorexia nervosa, with …
environmental factors. Given the progress of genomic discovery in anorexia nervosa, with …
Are trans diagnostic models of eating disorders fit for purpose? A consideration of the evidence for food addiction
J Treasure, M Leslie, R Chami… - European Eating …, 2018 - Wiley Online Library
Explanatory models for eating disorders have changed over time to account for changing
clinical presentations. The transdiagnostic model evolved from the maintenance model …
clinical presentations. The transdiagnostic model evolved from the maintenance model …
Examination of the shared genetic basis of anorexia nervosa and obsessive–compulsive disorder
Z Yilmaz, M Halvorsen, J Bryois, D Yu… - Molecular …, 2020 - nature.com
Anorexia nervosa (AN) and obsessive–compulsive disorder (OCD) are often comorbid and
likely to share genetic risk factors. Hence, we examine their shared genetic background …
likely to share genetic risk factors. Hence, we examine their shared genetic background …