Quercetin induces cytotoxicity and apoptosis, reduces metastasis and drug resistance in oral cancer cells

N Li, J Wang - Turkish Journal of Biochemistry, 2023 - degruyter.com
Quercetin is a plant flavonol from the flavonoid group of polyphenols or can also be
formulated as a synthetic supplement chemically. Approximately 80% of people in Africa and …

Epithelial transport of Noscapine across cell monolayer and influence of absorption enhancers on in vitro permeation and bioavailability: implications for intestinal …

MB Chougule, AR Patel, R Patlolla… - Journal of drug …, 2014 - Taylor & Francis
The purpose of this study was to investigate the permeation of Noscapine (Nos) across the
Caco-2 and Madin–Darby canine kidney (MDCK) cell monolayers and to evaluate the …

Nonimmunosuppressive chemotherapy: EM011-treated mice mount normal T-cell responses to an acute lymphocytic choriomeningitis virus infection

R Aneja, V Kalia, R Ahmed, HC Joshi - Molecular cancer therapeutics, 2007 - AACR
Myelosuppression and associated immunosuppression are major problems in cancer
chemotherapy. Thus, infection remains a significant source of morbidity and mortality during …

The inhibitory effect of noscapine on the in vitro cathepsin G-induced collagen expression in equine endometrium

A Amaral, C Fernandes, A Szóstek-Mioduchowska… - Life, 2021 - mdpi.com
Cathepsin G (CAT) is a protease released by neutrophils when forming neutrophil
extracellular traps that was already associated with inducing type I collagen (COL1) in …

那可丁衍生物合成及其作为微管干扰药物的生物学评估(英文)

戴厚玲, 郑剑斌, 林敏, 郑静, 周福生, 董肖椿, 郭磊… - 药学学报, 2012 - cqvip.com
以2-羟基-3-甲氧基苯甲醛为原料, 经13 步反应合成了26 个那可丁衍生物. 以HL-60
细胞为靶细胞, 采用MTT 法进行了初步的体外抗肿瘤活性研究. 结果表明, 大多数化合物对HL-60 …

小檗碱对人乳腺癌MDA-MB-231 生长抑制作用不经PPARγ 介导(英文)

章涛, 张潜, 陈代雄, 周岐新 - 中成药, 2009 - cqvip.com
目的: 探讨小檗碱对人乳腺癌细胞MDA—MB-231 体外生长的影响及其与PPARγ 受体的关系.
方法: 采用噻唑蓝(MTT) 法检测小檗碱对MDA-MB-231 细胞的生长抑制效应; TUNEL …

Apoptotic And Antiangiogenic Effects of Noscapine In Human Lung Cancer (A549) Cells

İ İslam, A Karagöz, H AYTUĞ, İ BULDUK… - Celal Bayar …, 2022 - dergipark.org.tr
Objective: Lung cancer, one of the most important health problems today, is the most
common type of cancer that causes death in both women and men. Although A549 lung …

[PDF][PDF] Synthesis and biological evaluation of noscapine analogues as microtubule-interfering agents

H Dai, J Zheng, M Lin, J Zheng, F Zhou, X Dong, L Guo… - 药学学报, 2012 - researchgate.net
A series of noscapine analogues have been synthesized via 13-step reaction starting from 2-
hydroxy-3-methoxybenzaldehyde. Anti-tumor activities of these compounds were evaluated …

[PDF][PDF] Novel combination of Vincristine and COX-2 Inhibitor Nimesulide provides synergistic anti-proliferative and pro-apoptotic effects in KOSC-2 oral squamous …

Z Yuan, D Chen, X Chen, Y Wei - International Journal of Clinical & …, 2016 - e-century.us
Oral cancer is one of the most common malignant tumors in head and neck cancer.
Vincristine (VCR) is an antimitotic agent widely used for cancer treatment. Nimesulide (NIM) …

[PDF][PDF] Chemistry & Biology Interface

M Tripathi, PL Reddy, DS Rawat - Chemistry & Biology, 2014 - cbijournal.com
Noscapine, a phthalideisoquinoline alkaloid, originally supposed to be a medicinally
insignificant constituent of the opium poppy until the discovery of its anti-tussive properties in …