Unraveling the brain regulation of appetite: lessons from genetics

GSH Yeo, LK Heisler - Nature neuroscience, 2012 - nature.com
… has been made with genome-wide association studies. Such … suggest that the major energy
homeostatic function of leptin … Further investigation of critical sites of leptin action implicated

[HTML][HTML] Shared genetic etiology and causality between body fat percentage and cardiovascular diseases: a large-scale genome-wide cross-trait analysis

Z Zhuang, M Yao, JYY Wong, Z Liu, T Huang - BMC medicine, 2021 - Springer
… Our findings suggest that BF% and CVDs have shared genetic … − 18 ), which is involved in
the leptin signaling pathway and its … study were obtained from genome-wide association study

[HTML][HTML] Genome-wide DNA methylation profiling in anorexia nervosa discordant identical twins

C Iranzo-Tatay, D Hervás-Marín, LM Rojo-Bofill… - Translational …, 2022 - nature.com
… In this regard, multiple lines of evidence suggest that … locus [38]. Regarding other metabolic
traits, our work pointed towards two genes that GWAS studies have described to be involved

Genetics of Eating Disorders

H Anke, V Anna-Lena - Current Psychiatry Reports, 2013 - search.proquest.com
… The latter also comprise genome-wide association studies (… [40] and thus genes involved
in weight regulation have been … leptin levels (adjusted for BMI and/or fat mass) as suggested

Pubertal timing and body mass: genes involved

DL Cousminer - Current Opinion in Endocrine and Metabolic Research, 2020 - Elsevier
… variation in these traits implies that their underlying molecular … Overlapping loci point
toward genes involved in both central … Large-scale genome-wide association studies (GWAS), …

[HTML][HTML] Alternative frameworks for advancing the study of eating disorders

SA Stern, CM Bulik - Trends in neurosciences, 2020 - cell.com
… In this opinion, we suggest that recent knowledge gleaned from … Genome-wide association
study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa. …

[HTML][HTML] A critical analysis of eating disorders and the gut microbiome

SM Terry, JA Barnett, DL Gibson - Journal of eating disorders, 2022 - Springer
… Here we provide a critical analysis of the field, suggest practical … a genome wide association
study identified eight significant loci for AN [17] and epigenetics has also been implicated in …

Stem cell models for context-specific modeling in psychiatric disorders

C Seah, LM Huckins, KJ Brennand - Biological Psychiatry, 2023 - Elsevier
… fine-map genome-wide association study loci and validate their … between genotype and gene
expression suggest a role for … especially been implicated as a cross-disorder risk factor (33)…

[PDF][PDF] Genetics of Eating Disorders: A Candidate Gene and a Genome-wide Association Approach

S Helder - 2012 - kclpure.kcl.ac.uk
… that suggests that they endorse you or your use of the work). • … she was involved in the quality
control of genome-wide genetic … Several studies have attempted to detect susceptibility loci

[HTML][HTML] The ghrelin-AgRP neuron nexus in anorexia nervosa: Implications for metabolic and behavioral adaptations

M Méquinion, CJ Foldi, ZB Andrews - Frontiers in Nutrition, 2020 - frontiersin.org
… from a recent genome-wide association study that revealed … knowledge, no study has
directly implicated altered plasma … availability, suggesting that the unfulfilled hunger signal from …