Monitoring of BCR-ABL expression using real-time RT-PCR in CML after bone marrow or peripheral blood stem cell transplantation

M Eder, K Battmer, S Kafert, A Stucki, A Ganser… - Leukemia, 1999 - nature.com
Interferon alpha 2b (IFN) combined with cytarabine versus interferon alone in chronic
myelogenous leukemia. … leukemia by quantitative polymerase chain reaction. …

Randomized comparison of interferon α and hydroxyurea with hydroxyurea monotherapy in chronic myeloid leukemia (CML-study II): prolongation of survival by the …

R Hehlmann, U Berger, M Pfirrmann, A Hochhaus… - Leukemia, 2003 - nature.com
… the chronic phase of chronic myelogenous leukemia (CML Study … of CML patients treated
with interferon alpha monitored by … -α therapy by competitive polymerase chain reaction. Blood …

[HTML][HTML] The significance of major and stable molecular responses in chronic myeloid leukemia in the tyrosine kinase inhibitor era

IZ Renault, V Scholl, R Hassan, P Capelleti… - Revista brasileira de …, 2011 - SciELO Brasil
… Quantitative polymerase chain reaction is used to monitor … after treatment with interferon-alpha
because Brazil public … to discriminate between the competing possibilities of achieving an …

Chronic myeloid leukemia: current application of cytogenetics and molecular testing for diagnosis and treatment

A Tefferi, GW Dewald, ML Litzow, J Cortes… - Mayo Clinic …, 2005 - Elsevier
… for monitoring minimal residual disease after successful therapyPolymerase chain reaction
involves the amplification of … well as competitive nested RT-PCR for disease monitoring.157, …

Current and emerging tests for the laboratory monitoring of chronic myeloid leukaemia and related disorders

DM Ross, TP Hughes - Pathology, 2008 - Taylor & Francis
… shown that there is competition between the Ph positive and Ph negative clones, so that
the emergence of Ph negative clonal abnormalities may reflect the efficient suppression of the …

How we monitor the therapy effectiveness in patients with chronic myeloid leukemia-A Single center experience

S Mešanović, A Žugić-Jahić, S Hasić, V Simendić… - Genetics & …, 2023 - genapp.ba
… The quantitative real-time polymerase chain reaction method (… adherence in chronic
myelogenous leukemia in the chronic … after failure of interferon-alpha treatment. Blood 1;111(3):…

Monitoring CML patients responding to treatment with tyrosine kinase inhibitors: review and recommendations for harmonizing current methodology for detecting BCR …

T Hughes, M Deininger, A Hochhaus, S Branford… - Blood, 2006 - ashpublications.org
… The use of real-time quantitative polymerase chain reaction (… In 1993 Cross and colleagues
introduced a competitive … of BCR-ABL are necessary to monitor the performance of the assay, …

Chronic myeloid leukemia: 2020 update on diagnosis, therapy and monitoring

E Jabbour, H Kantarjian - American journal of hematology, 2020 - Wiley Online Library
… Baseline reverse transcriptase-polymerase chain reaction is … It acts via competitive inhibition
at the ATP-binding site of the … Given the equivalent efficacy and lower toxicity of lower dose …

[HTML][HTML] Treatment-Free Remission—A New Aim in the Treatment of Chronic Myeloid Leukemia

P Kwaśnik, K Giannopoulos - Journal of Personalized Medicine, 2021 - mdpi.com
… The role of modern droplet digital polymerase chain reaction (… to the treatment of TKI, then
interferon alpha (IFN-α) therapy is … to the patient allows for careful monitoring of the patient. …

Human leukocyte antigen-B phenotype and minimal residual disease in chronic myeloid leukemia patients treated with imatinib: Is there an association?

E Hadad, A Ehsanpour, T Vosoughi… - Clinical Cancer …, 2020 - search.ebscohost.com
… ) in chronic myelogenous leukemia (CML) patients treated … by real‑time polymerase chain
reaction technique. Results: No … of the drugs used to treat cancer such as interferonalpha (…