Mesenchymal stem cells in health and disease

A Uccelli, L Moretta, V Pistoia - Nature reviews immunology, 2008 - nature.com
… (straight, solid arrows) towards the mesodermal lineage. The … for the first time to treat children
with severe osteogenesis … issues will allow for the translation of our basic knowledge of …

Off-the-shelf tissue-engineered vascular conduits: clinical translation

ES Fioretta, L von Boehmer, M Generali… - Tissue-Engineered …, 2020 - Springer
cell sources – including induced pluripotent stem cells – and … used for the treatment of CHD
is polytetrafluoroethylene (… stem cells that could differentiate towards multiple cell phenotypes …

Cell therapy for the treatment of coronary heart disease: a critical appraisal

KC Wollert, H Drexler - Nature Reviews Cardiology, 2010 - nature.com
… , stem cell therapy instead of bone marrow cell (BMC) therapy, … A trend towards a greater
incidence of arrhythmias was, … Translation of these concepts from disease models into the …

Mechanical stimulation of mesenchymal stem cell proliferation and differentiation promotes osteogenesis while preventing dietary‐induced obesity

YK Luu, E Capilla, CJ Rosen, V Gilsanz… - Journal of bone and …, 2009 - academic.oup.com
Translating the ability of LMMS to bias bone formation over fat … for fractures in normally active
children and adolescents, it … a distinct bias toward osteogenesis after 6 wk, translating at 12 …

Spotlight on HDL biology: new insights in metabolism, function, and translation

DJ Rader - Cardiovascular Research, 2014 - academic.oup.com
… not been shown to be protective against CHD. However, because … men with CHD treatment
with immediate-release niacin … For example, cholesterol efflux from hematopoietic stem cells

Efficient derivation of human cardiac precursors and cardiomyocytes from pluripotent human embryonic stem cells with small molecule induction

XH Parsons, YD Teng, JF Parsons, EY Snyder… - JoVE (Journal of …, 2011 - jove.com
… pluripotent stem cells towards specialized functional cells. (A) … developmental study and
clinical translation has been how … associated with human congenital heart disease (CHD), the …

A strong regenerative ability of cardiac stem cells derived from neonatal hearts

DL Simpson, R Mishra, S Sharma, SK Goh… - Circulation, 2012 - Am Heart Assoc
… address the structural deficiencies of congenital heart disease. … Differentiation of CDCs toward
cardiac lineages was … augmentation of proangiogenic factors translated to increase blood …

[HTML][HTML] Biological scaffolds for congenital heart disease

AG Harris, T Salih, MT Ghorbel, M Caputo, G Biglino… - Bioengineering, 2023 - mdpi.com
… , most of them failed to be successfully translated in this life-… in paediatric CHD treatment,
warning against the application … primary cell types have a limited lifespan, stem cells are self-…

[HTML][HTML] Drug and cell delivery for cardiac regeneration

CL Hastings, ET Roche, E Ruiz-Hernandez… - Advanced drug delivery …, 2015 - Elsevier
… in the treatment of cardiovascular disease. The most effective … However, clinical translation
of regenerative therapeutics … trials, cardiac stem cells, or cardiopoietic stem cells have shown …

[PDF][PDF] Monoclonal antibody-mediated targeting of CD123, IL-3 receptor α chain, eliminates human acute myeloid leukemic stem cells

L Jin, EM Lee, HS Ramshaw, SJ Busfield, AG Peoppl… - Cell stem cell, 2009 - cell.com
… isolated AML CD34+ CD38À cells in vitro and reduced … therapeutic monoclonal antibody
(mAb) targeting of AML-LSCs and for translation of in vivo preclinical research findings toward a …