Biointerface Characterization by Nonlinear Optical Spectroscopy

W Sun, S Wang, X Han - Nanophotonics in Biomedical Engineering, 2021 - Springer
… able to employ second-order nonlinear optical techniques, sum … changes and spatial
distribution of collagen in the tail skin of … detection of chiral molecules, and the chiral response …

Nonlinear Optical Microscopy and Spectroscopy Studies of Biological Molecules

JC Hsu - 2017 - escholarship.org
… study of collagen second order nonlinear susceptibility tensor terms… collagen, it is unclear
what the origin of the second order … have pointed to either the amide group of the peptide bond …

Polarization-resolved second harmonic generation microscopy with a four-channel Stokes-polarimeter

N Mazumder, J Qiu, MR Foreman, CM Romero… - Optics express, 2012 - opg.optica.org
… incoming light and the second-order hyper polarizability of the … nonlinear optical crystal and
collagen type-I, respectively. … The chirality in collagen affects the SH polarization, resulting in …

C–H stretch for probing kinetics of self-assembly into macromolecular chiral structures at interfaces by chiral sum frequency generation spectroscopy

Z Wang, L Fu, ECY Yan - Langmuir, 2013 - ACS Publications
… Unlike the amide I and the N–H stretch, the chiral C–H stretch … origins of the remarkable
chiral sensitivity of second-order … In situ nonlinear optical spectroscopic study of the structural

Organized chromophoric assemblies for nonlinear optical materials: towards (sub) wavelength scale architectures

J Xu, S Semin, T Rasing, AE Rowan - Small, 2015 - Wiley Online Library
… studied biological fibrillar collagen structures, considering the … the second-order optical
nonlinearity of the polymer structure. … The effect of the chirality of the polymers on the surface SHG …

Examining lysyl oxidase-like modulation of collagen architecture in 3D spheroid models of idiopathic pulmonary fibrosis via second-harmonic generation microscopy

DS James, CJ Brereton, DE Davies… - … Biomedical Optics, 2021 - spiedigitallibrary.org
… We probed the net chirality of the collagen using the SHG-CD … amide I band is sensitive to
the collagen secondary structure. … He specializes in developing nonlinear optical approaches …

Multimodal Nonlinear Vibrational Hyperspectral Imaging

J Wagner, Z Wu, W Xiong - 2023 - chemrxiv.org
… On the other hand, structural imaging can be realized through second-order … such as
collagen and celliluse.When using SHG and VSFG to study these tissues, its anisotropic chiral

Second harmonic generation microscopy: principles and applications to disease diagnosis

PJ Campagnola, CY Dong - Laser & Photonics Reviews, 2011 - Wiley Online Library
… that chirality leads to an enhancement of the second order … helix in OI collagen may display
different chiral contributions in … groups associated with the amide I band was consistent with …

Multimodal nonlinear optical microscopy

S Yue, MN Slipchenko, JX Cheng - Laser & photonics reviews, 2011 - Wiley Online Library
… SFG is a second-order NLO process in which two incident … the first optically active SFG
microscope, which allows chirality-… 5, SFG imaging specifically recognizes dense wavy collagen

Imaging of protein crystals with two-photon microscopy

P Padayatti, G Palczewska, W Sun, K Palczewski… - Biochemistry, 2012 - ACS Publications
Second-order nonlinear optical imaging of chiral crystals (… for identifying structurally
ordered proteins such as collagen, … of proteins and other amine/amide-containing polymers: (i) …