Design of pH-sensitive methotrexate prodrug-targeted curcumin nanoparticles for efficient dual-drug delivery and combination cancer therapy
J Xie, Z Fan, Y Li, Y Zhang, F Yu, G Su… - International journal of …, 2018 - Taylor & Francis
Aim We designed acid-labile methotrexate (MTX) targeting prodrug self-assembling
nanoparticles loaded with curcumin (CUR) drug for simultaneous delivery of multi …
nanoparticles loaded with curcumin (CUR) drug for simultaneous delivery of multi …
Recent advances in curcumin-loaded biomimetic nanomedicines for targeted therapies
F Lei, P Li, T Chen, Q Wang, C Wang, Y Liu… - Journal of Drug Delivery …, 2023 - Elsevier
Curcumin shows excellent anti-inflammatory and anti-tumor activities, but its solubility,
stability, and bioavailability are poor. Nanoparticle delivery systems can be used to enhance …
stability, and bioavailability are poor. Nanoparticle delivery systems can be used to enhance …
Curcumin, its derivatives, and their nanoformulations: Revolutionizing cancer treatment
I Ahmad, S Ahmad, A Ahmad… - Cell Biochemistry …, 2024 - Wiley Online Library
Curcumin is a natural compound derived from turmeric and can target malignant tumor
molecules involved in cancer propagation. It has potent antioxidant activity, but its …
molecules involved in cancer propagation. It has potent antioxidant activity, but its …
Curcumin-based nanomedicines: A promising avenue for brain neoplasm therapy
M Banazadeh, B Behnam, NA Ganjooei… - Journal of Drug Delivery …, 2023 - Elsevier
Brain tumor ranks as the tenth most common cause of death among individuals with cancer
globally, and those diagnosed with this condition continue to experience unfavorable …
globally, and those diagnosed with this condition continue to experience unfavorable …
Design of curcumin loaded carbon nanodots delivery system: Enhanced bioavailability, release kinetics, and anticancer activity
DM Arvapalli, AT Sheardy, K Allado… - ACS Applied Bio …, 2020 - ACS Publications
Despite the potential health benefits of curcumin, such as antioxidant, anticancer, anti-
inflammatory, and antimicrobial properties, its usage is limited by poor bioavailability and …
inflammatory, and antimicrobial properties, its usage is limited by poor bioavailability and …
Evaluation of multilayer coated magnetic nanoparticles as biocompatible curcumin delivery platforms for breast cancer treatment
Biocompatible multi-layer iron oxide magnetic nanoparticles (MNPs) for drug delivery
applications with increased loading capacity, sustained sensitive release profile, and high …
applications with increased loading capacity, sustained sensitive release profile, and high …
Synergistic effect of the anti-PD-1 antibody with blood stable and reduction sensitive curcumin micelles on colon cancer
F Gong, JC Ma, J Jia, FZ Li, JL Wu, S Wang, X Teng… - Drug Delivery, 2021 - Taylor & Francis
Abstract Curcumin (1, 7-bis (4-hydroxy-3-methoxyphenyl)-1, 6-heptadiene-3, 5-dione) is a
potent anticancer drug with versatile biological activities, while the clinical translation of …
potent anticancer drug with versatile biological activities, while the clinical translation of …
Curcumin-loaded galactosylated BSA nanoparticles as targeted drug delivery carriers inhibit hepatocellular carcinoma cell proliferation and migration
Y Huang, L Hu, S Huang, W Xu, J Wan… - International Journal …, 2018 - Taylor & Francis
Background The main objective of this study was to develop novel BSA nanoparticles (BSA
NPs) for improving the bioavailability of curcumin as an anticancer drug, and those BSA NPs …
NPs) for improving the bioavailability of curcumin as an anticancer drug, and those BSA NPs …
Curcumin delivery by methoxy polyethylene glycol–poly (caprolactone) nanoparticles inhibits the growth of C6 glioma cells
As a potential anticancer agent, curcumin (Cum) has been reported for its chemopreventive
and chemotherapeutic activity in a series of cancers through influencing cell cycle arrest …
and chemotherapeutic activity in a series of cancers through influencing cell cycle arrest …
Toxicity Evaluation and Controlled-Release of Curcumin-Loaded Amphiphilic Poly-N-vinylpyrrolidone Nanoparticles: In Vitro and In Vivo Models
AL Luss, DV Bagrov, AV Yagolovich, EV Kukovyakina… - Pharmaceutics, 2023 - mdpi.com
Curcumin attracts huge attention because of its biological properties: it is antiproliferative,
antioxidant, anti-inflammatory, immunomodulatory and so on. However, its usage has been …
antioxidant, anti-inflammatory, immunomodulatory and so on. However, its usage has been …