Studies of four novel diphenylbutylpiperazinepyridyl derivatives on release and inhibition of reuptake of dopamine, serotonin and noradrenaline by rat brain in vitro

E Pettersson - European journal of pharmacology, 1995 - Elsevier
Four novel diphenylbutylpiperazinepyridyl derivatives (FG5865 (2-[4-[4, 4-bis (4-
fluorophenyl) butyl]-1-piperazinyl]-3-pyridinecarboxamide), FG5891 (2-[4-[4, 4-bis (4 …

Differences in brain 5‐HT transporter dissociation rates among animal species

I Erreboe, P Plenge, ET Mellerup - Pharmacology & toxicology, 1995 - Wiley Online Library
The potential of using receptor‐ligand dissociation rates as a model for investigating
molecular changes in receptors was tested using the dissociation of [3H] citalopram,[3H] …

Brain serotonin subsystem complexity and receptor heterogeneity: therapeutic potential of selective serotonin agonists and antagonists

KP Lesch, CS Aulakh, DL Murphy - Clinical Pharmacology in Psychiatry …, 1993 - Springer
Gaddum and Picarelli (1957) initially suggested the existence of more than one serotonin (5-
HT) receptor over 30 years ago. Subsequently, neurophysiological, pharmacological, and …

Local cerebral metabolic effects of the novel cocaine analog, WF‐31: Comparisons to fluoxetine

LJ Porrino, M Miller, AA Hedgecock, C Thornley… - Synapse, 1997 - Wiley Online Library
The effects of the acute administration of the selective serotonin uptake inhibitor, fluoxetine,
on rates of local cerebral glucose utilization in rats were compared to those of the novel …

Alterations in behavior and opioid gene expression induced by the novel tropane analog WF-31

JB Daunais, SL Hart, A Hedgecock-Rowe… - Molecular brain …, 1997 - Elsevier
The effects of the acute administration of the serotonin-selective tropane analog,[2β-
propanoyl-3β-(4-isopropylphenyl)-tropane, WF-31, on spontaneous locomotor activity were …

Valoración cuantitativa del SPECT con FP-CIT. Importancia del área de referencia

SJO Lozano, MDM del Valle Torres, ER Moreno… - Revista Española de …, 2010 - Elsevier
Objetivo El objetivo del presente estudio es comparar diversos índices de captación entre
actividad específica/inespecífica para determinar la existencia de parkinsonismo …

In search of black bile: do antidepressants act by changing endogenous endocoids in the depressed patient?

BE Leonard - Journal of Psychopharmacology, 1993 - journals.sagepub.com
High affinity binding sites for psychotropic drugs may represent recognition sites for
endogenous ligands. For example, it is well established that opioid receptors bind …

Endocoids in depression: do antidepressants alter endocoids that affect the serotonergic system?

BE Leonard - Progress in Neuro-Psychopharmacology and …, 1993 - Elsevier
Studies undertaken over the last decade have shown that factors are present in in brain
extacts, cerebrospinal fluid and plasma that impede the transport of tritiated 5HT into cortical …

Dopamine Reuptake Sites: The Issues

E Salmon - Brain Dopaminergic Systems: Imaging with Positron …, 1991 - Springer
ABSTRACf. Although the mechanism of monoamine reuptake is a well established important
phenomenon, the singleness or coexistence of monoamine transporter and reuptake …

[PDF][PDF] Platelet [3H] imipramine and [3H] paroxetine binding sites in depression, anxiety and stress, and their association with symptoms and risk factors for depression

LJ Iny - 1992 - spectrum.library.concordia.ca
During the past several years there has been growing interest in the phenomenological and
neurobiological relationship between depression and anxiety. This interest follows from …